Test 2 - Cell Architecture L4 - cell migration

Question 1

Po co cell migrate During embryo development

Answer 1

to generate different tissues and organs (morphogenesis)

Question 2

Po co cell migrate During the wound healing

Answer 2

to close wounds

Question 3

Po co cell migrate During immune response

Answer 3

to follow and attack pathogens

Question 4

Po co cell migrate In cancer

Answer 4

to invade healthy tissues

Question 5

W co Neural Crest przechodzi jeśli chodzi o Cranial (3)

Answer 5

connective tissue, cartilage and bone, neurons and glia of cranial ganglia

Question 6

Z czego Neural Crest pochodzi

Answer 6

From Dorsal part of Neural tube

Question 7

W co Neural Crest przechodzi jeśli chodzi o Trunk (3)

Answer 7

pigment cells, sensory neurons and glia, sympatho-adrenal cells,

Question 8

Cell-cell contact leads to ….

Answer 8

Cell contact ->RhoA activation ->collapse of cell protrusion ->Direction (Rac inhibition)

Question 9

Co mają na zakończeniach leading cells of neural crest cells?

Answer 9

Rac actina

Question 10

Opisz Neural Crest Migration Program

Answer 10

EMT, 
delamination, 
stereotypic migration,
target site entry,
colonization

Question 11

Opisz Melanoma Metastasis

Answer 11

phenotypic interconversion,
separation from primary mass, 
migration/ dissemination,
target site entry,
metastatic colonization,