Test 2 Flashcards
- a fluid connective tissue; formed elements are
Blood
- straw colored fluid containing dissolved substances 55%
plasma
- leukocytes and platelets 1%
buffy coat
- red blood cells and hematocrit 45% of bood they have the following characteristics: they are biconcave disks anucleate (no nucleus) large surface volume no mitochondria mostly hemoglobin 120 day lifespan
erythrocytes
___ are white blood cells
leukocytes
_____ are cell fragments required for clotting called thrombocytes
platelets
Females have ___L of blood while males have __L of blood
4-5, 5-6
Blood functions:
Distribution
Oxygen, nutrients, waste and hormones
Regultion
body temperature, pH buffer, fluid volume
Protection
clot formation and prevention of infections
- blood cell formation
Hematopoiesis
- mitotic stem cell of all formed elements
Hemocytoblast
- red iron containing pigment which binds oxygen
heme
- protein which binds carbon dioxide
globin
- a hormone made by the kidneys that stimulates red blood cell production (RBC)
erythropoietin
____ destroys worn out red blood cells
Spleen
___ is converted to bilirubin and excreted in bile by liver, iron is recycled, globin is hydrolyzed (digested) to amino acids for reuse
Heme
- granular cytoplasm in white blood cells, granular cytoplasm is stained with wright’s stain, nuclei are lobed, end with ‘phil’
granulocytes
________ (most abundant white blood cell) polymorphonuclear (many forms of nucleus)
3-6 lobes
active phagocytes of bacteria
neutrophils
- bluish red nucleus 2 lobes cytoplasmic granules are red kill parasitic worms active during allergic reaction
eosinophils
_______ (least abundant white blood cell) purplish black
rare, releases histamine which is an inflammatory chemical that promotes chemotaxis of white blood cells
releases heparin which is an anticoagulant
basophils
- are not granular white blood cells, lack visible granules, nuclei are spherical shaped or kidney shaped, end with “cyte”
agranulocytes
- found in the spleen and lymph nodes
important in immune response
large nucleus
t-lymphocytes act against viruses and tumoral cells
b-lymphocytes become plasma cells that make antibodies
antibody Ab, Antigen Ag
lymphocytes
- u shaped nucleus
differentiate into macrophages in tissue
involved in the cleanup of debris at the end of infections
monocytes
White blood cells use _______ - amoeboid movement and positive chemotaxis to migrate toward damaged tissues
diapedesis
- white blood cells increase due to infection
Leukocytosis
- production of white blood cells, occur in bone marrow
life span of about 10 days if not used in clotting
leukopoiesis
- cytoplasmic fragments used for clotting
bluish color
Platelets
- 90% water and proteins, nutrients, gas
Plasma
_____ is a major blood protein which is important in creating osmotic pressure gradients
Albumin
_____ functions in immune response
immunoglobulin
Red blood cell plasma membranes have highly specific _____ or agglutinogens that cause clumping on the surface of red blood cells
antigens
the Rh factor is also called ____
Antigen D
85% of americans are Rh _____ (agglutinogen D)
positive
___ red blood cells have Rh antigen and no anti Rh antibodies
Rh+
____ red blood cells have neither Rh antigens or antibodies until exposed to Rh+ blood
Rh -
The immune system produces the _______
antibodies