Test 1: Specific Cells & Indications Flashcards
What can cause Heinz body formation
in dogs?
Onion/garlic
Cephalosporins
Zinc (penny) toxicosis
In horses,
Phenothiazines
and
Wilted Red Maple Leaves
can cause the formation of this
Heinz bodies
What can cause Heinz body formation
in cattle?
Kale and onion ingestion
Which species is particularly vulnerable to
copper toxicosis which can result in
Heinz body formation?
Sheep (released when stressed)
What can cause Heinz body formation
in a cat?
Onion/Garlic
Acetaminophin!
What is an
Acanthocyte
indicative of in a dog? In a cat?
Dog- Hemangiosarcoma
Cat- Hepatic lipidosis
What could potentially cause
Schistocyte formation?
Hemangiosarcoma or DIC
What is a spherocyte indicative of, especially
if found in a dog?
IMHA
Keratocytes
are only seen in this disease
Iron-Deficiency Anemia
In what species is
basophilic stippling
a normal finding?
Ruminants
In small animals,
what is basophilic stippling
indicative of?
Lead poisoning
What are 3 things that can
account for Nucleated RBCs?
Regenerative Anemia
Splenectomy
Corticosteroids
Howell-Jolly Bodies
indicate what organ dysfunction?
Spleen is non-functional
or
Splenectomy
What type of anemia
is indicated by presence of
Polychromasia?
Regenerative Anemia
(Blood loss or blood destruction)
A dog gets bit by a rattlesnake.
What type of cell do you expect to see
upon hematology?
Echinocytes
Rouleaux formation
is normal in which species?
Horses
Rouleaux formation is caused by an
increase in _______
due to antigenic stimulation
secondary to inflammation
globulin
In a dog,
Rouleaux formation can be confused with
Agglutination. What is indicated by each?
Rouleaux formation = Ehrlichia
Agglutination = IMHA
Giant platelets and RBCs with central pallor
are indicative of this disease
Iron-Deficiency Anemia
What is aniscytosis?
What can it tell you?
A variation in RBC size
If RBCs are larger, Macrocytic= Regenerative anemia
If RBCs are smaller, Microcytic= Iron-Def anemia
Basophilia, vacuolation of the cytoplasm, and
presence of Dohle bodies are indicative of
Neutrophil Toxic Change
which means INFLAMMATION
What type of morphological change is seen
in neutrophils that are in circulation too long?
Hypersegmented Neutrophils
Hypersegmented neutrophils are
caused by what 2 processes?
Cushing’s Disease (increased endogenous steroids)
Steroids (Prednisone) (exogenous steroids)
A plasma cell that has spherical inclusions of
clumped immunoglobulins that
indicate either
Chronic Inflammation or B-Cell Lymphoma
Mott Cells
with Russel Bodies
What is a ghost cell and what does it
indicate?
An empty RBC, indicates IMHA
If you see metamyelocytes, you can be sure
that severe ______ is present
Metamyelocytes are very immature neutrophils
SEVERE inflammation
If you see large-SIZED lymphocytes,
what is your probable diagnosis?
Lymphoid leukemia
If you see large monocytes, what can be causing it?
Stress or Inflammation
The presence of eosinophils
indicates these 3 conditions
Immune-complex reaction
Allergic inflammation
Parasites
What type of change would be seen in
neutrophils if the host has abscesses or septicemia?
Neutrophil degeneration
A red blood cell with hypochromasia
is indicative of
Iron-deficiency anemia
RBC agglutination is indicative of IMHA,
where this antibody attaches to the RBCs
IgM
What are Dohle bodies? What are their implications?
Dohle bodies are neutrophil intracellular inclusions
made of aggregated ribosomes (RER)
They indicated Toxic Change which means
INFLAMMATION is present
