Test 1: CBC Values and Indications Flashcards
Increased PCV
Dehydration
Decreased PCV
Anemia
Increased reticulocytes
Regenerative anemia
(Blood loss or blood destruction)
0 reticulocytes
Non-regenerative anemia
(Bone marrow is not working)
Increased TP
Blood destruction
Decreased TP
Blood loss
(hemorrhaging)
Which species would you NOT
perform a reticulocyte count in?
Why?
HORSES
They don’t produce retics
A decrease in lymphocytes is due to stress,
caused by this hormone
Cortisol- cytotoxic to lymphs
An increase in lymphocytes indicates
excitement, caused by this hormone.
What can you do to check if you’re correct?
Epinephrine = Excitement in cats
Check glucose- also high with excitement
What is the only reason that the
albumin level would be increased?
DEHYDRATION
Increases in BUN (blood urea nitrogen) and Creatinine
are indicative of
Kidney dysfunction
What is the most probable cause
of a decreased phosphorus level?
Diabetes
Check GLU levels to be sure:
high GLU = low phos
in diabetes
What are two reasons you could have
for seeing an increased GLU level?
Diabetes
Excitement in cats
What are the 3 reasons for seeing an
increase in Tbili (total bilirubin)?
What is the mechanism of insult
in regards to the liver?
Pre-hepatic- RBC destruction (check TP is increased)
Hepatic- Liver dysfunction (check ALT is increased)
Post-hepatic- Bile duct obstruction
(check AlkPhos is increased)
Increased cholesterol is often seen in animals
with __________, which is also indicated by
low phosphorus and high glucose levels
Diabetes
What is ALT? What does it mean if it’s
increased?
ALT (liver enzyme)
An increase = Liver dysfunction or Anemia
What can cause an increase in Alkaline Phosphatase?
Bile duct obstruction
What would you check to confirm a
metabolic acidosis
(commonly seen in animals with Diabetes)?
Check to see if the TCO2 (total bicarb)
is LOW
An increase in unmeasured anions results
in an increased Anion Gap.
What anions are not being measured?
Ketones (Diabetes)
Lactic Acid (Lactic acidosis)
Urine Specific Gravity that is
between 1.008 and 1.012
is low and indicates dysfunction in
The kidneys!
Can’t concentrate the urine
What is the MCV (Mean Cell Volume)
and what does a deviation from the normal
suggest?
MCV is the average size of RBCs in an animal
Increase= Macrocytic Anemia
(regenerative: blood loss/destruction)
Decrease= Microcytic Anemia
(regenerative: Iron-deficiency anemia)
What can cause an erroneously high
MCHC level?
Lipemia
Heinz bodies
Intravascular hemolysis
What is an increase in Band Neutrophils
indicative of? What if bands are the only thing you
are seeing?
Increased bands= Inflammation
but if bands are the only thing you are seeing,
it’s Pelger-Huet Anomaly
(failure of the neutrophils to segment)
An increase in Segs (segmented neutrophils)
means you have a/an
__________ leukogram
Inflammatory
An increase in globulin means there is a
gammopathy.
What is a monoclonal gammopathy indicative of?
How about a polyclonal gammopathy?
Increased Globulin=
Monoclonal Gammopathy: Multiple Myeloma
Polyclonal Gammopathy: Canine Ehrlichiosis
An increase in the RDW signifies
Anemia
(Red Cell Distribution Width)