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Blood Bank Test 1 > Test 1 Immunoglobulins > Flashcards

Test 1 Immunoglobulins Flashcards

1
Q

Gamma heavy chain

A

IgG

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2
Q

Mu heavy chain

A

IgM

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3
Q

Alpha heavy chain

A

IgA

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4
Q

Epsilon heavy chain

A

IgE

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5
Q

Delta heavy chain

A

IgD

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6
Q

180,000 D molecular weight

A

IgG

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7
Q

900 kD molecular weight

A

IgM

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8
Q

400 kD molecular weight

A

IgA

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9
Q

180 molecular weight

A

IgE and IgD

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10
Q

IgG shape

A

monomer

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11
Q

IgM shape

A

pentamer

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12
Q

IgA shape

A

dimeric; monomer/polymer (2IgA molecules joined by J chain)

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13
Q

IgE shape

A

monomer (in serum)

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14
Q

IgD shape

A

monomer

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15
Q

Most clinically significant

A

IgG

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16
Q

Destroys antigen coated transfused red cells

A

IgG

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17
Q

Macrophage Fc receptors

18
Q

Reaction temp at 37 degrees

19
Q

Activates complement

A

IgG and IgM

20
Q

Crosses the placenta

21
Q

Hemlytic disease of the newborn

22
Q

Naturally occuring

23
Q

Interfers with detection of IgG anitbodies

24
Q

Primary immune response

25
Q

Subclasses IgM1, IgM2

26
Q

First immunoglobulin produced in fetus

27
Q

Antibodies in ABO blood system

28
Q

Confined to blood stream

29
Q

Antibody-antigen agglutination

30
Q

May enhance autoimmune RBC hemolysis

31
Q

Sound in secretions

32
Q

No bacteriocidal effects

33
Q

Localizes infectious agents

34
Q

Subclasses IgA1, IgA2

35
Q

Triggers cellular release of histamine

36
Q

Use antihistamines during transfusion to prevent allergic react/ anaphylaxis

37
Q

Shortests half life, highest catabolic rate, lowest synthesis rate

38
Q

Bound by Fc portion to basophils and mast cells

39
Q

Increased vascular permeability

40
Q

May relate to maturation/ differentiation of B cells

41
Q

No blood group antibodies

Blood Bank Test 1 (5 decks)

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