TEST 1 (GU studies,) Flashcards
Where IV Contrast is being used
??
Urinary system
Vascular System
CT/ MRI
A substance containing ions is called ___
ionic
Ion is ____
atom with + or - charge
cation ____ electrons
anion _____ electrons
loses
gains
what is ionization
separating neutral atom into ions
The # of osmoles of a solution is called ____
osmolality
what is osmoles
particles that contribute to osmotic pressure
what is required to stop osmosis
osmotic pressure
increased osmotic pressure = ____ osmotic events
increased
Osmosis is the movement of a solvent from ____ concentration to ____ concentration
low
high
What is the chain of events that happens when contrast is injected
increased osmoles –> increased chain of reactions –> body reacting more to maintain homeostasis
What contrast media is used for urography
Iodine
What does high atomic number of iodine indicate
high attenuation of X-ray beam and better visualization of structures
what is the structure of all iodinated contrast agents
benzene structure with 3 iodine atoms & 2 groups of amino acid
Iodine is a ____ element
opacifying
Iodine contrast agent is also referred as ____ molecule
tri-iodinated
What are 4 types of iodinated contrast
- Ionic - High Osmolar Contrast Media (HOCM)
- Nonionic - Low osmolar Contrast media (LOCM)
- Monomer
- Dimer
Which type of iodinated contrast does not contain charged ion
nonionic
Ionic contrast usually contains which charged component
positive (cation)
What is the role of cation in ionic contrast medium
increase solubility
What is the role of anion in ionic contrast medium
stabilize & detoxify
Injecting ionic contrast will ____ osmolality
increase
An ionic tri-iodinated monomer can increase the osmolality of plasma is considered _____
high-osmolar contrast media (HOCM)
Which type of iodinated contrast will decrease chance of reaction?
non-ionic & LOCM
Which type of iodinated contrast will increase chance of reaction?
ionic & HOCM
Which type of iodinated contrast is recommend for use as IV contrast injection
nonionic - LOCM
Why LOCM is preferred over HOCM
Pt less likely to have contrast medium reaction.
LOCA is nonionic so it doesn’t go through ionization so the molecule is intact –> lower osmoles –> decrease osmolality –> decrease chance of reaction. BUT there is an increase in concentration in the blood stream so the body doesn’t work as hard to maintain balance
Why monomer and dimer are used?
need to double check again
increase # of opacifying elements (iodine) per molecule to decrease amount of ___ to see vascular structures
What happened (molecular level) when the ion contrast is injected
ionization –> separate cation (salt) & anion –> increase osmolality -> increase osmotic events –> increase osmosis –> body tried to balance
What are the 3 things technologist must check for on patient’s chart before proceeding with the injection
- Blood urea nitrogen (BUN)
- Creatinine
- eGFR ( estimated glomerular filtration rate)
what are the 2 diagnostic indicators of kidney function
- Blood urea nitrogen (BUN)
- Creatinine
An increase in level of BUN and creatinine indicated ____
compromised kidneys –> cant be injected with contrast
What is normal creatinine level
0.6 - 1.5 mg/dL
what is normal BUN level
8-25 mg/ 100mL
what is normal eGFR level?
what is the ACR recommends?
> 60 mL/ min
<30 mL/ min has a risk for contrast
What is the most reliable diagnostic indicator on a pt’s chart [Urinary System]
eGFR
What are possible contraindications to iodine contrast (5)
- iodine sensitivity
- kidney problems (except stones)
- allergies
- prior reactions
- Diabetic
Patient whos taking ____ can be given iodine contrast only if their kidney function levels are within normal limit
metformin
What is Metformin
a drug for non-insulin dependent diabetes patient
What does metformin do ?
decrease hepatic glucose and increase body’s response to insulin
The patient can continue to use prior to or following contrast injection if the eGFR level is ____
30mL or greater
If there is evidence of AKI (acute kidney injury), what is the instruction for metformin use?
withheld prior to injection and for 48hours after injection
What are the common side effects that may occur after an IV injection (3)
- nausea
- metallic taste
- warm, flush feeling
Which medical equipment must be readily available whenever IV injection is performed
crash cart
What are two categories of contrast medium reaction
local
systemic
___ reactions affect specific region of the body
local
____ reactions do not affect site of injection but entire body or specific organ
systemic
Which categories of reactions can lead to significant complications
systemic
What are the 2 local reactions to contrast medium
extravasation & phlebitis
What is extravasation
contrast leak outside the vessel and fills the surrounding soft tissue surrounding the access site (BLOW VEIN)
extravasation aka ____
infiltration
What caused extravasation
venous access is lost
What is the common protocol for extravasation? (4)
Notify the nurse/physician
Elevate the affected arm above the heart
Cold and warm compress
Document
What is phlebitis
inflammation of vein
3 categories for systemic reactions
mild, moderate, severe
Which of the following is considered as a moderate reaction?
a. anxiety
b. hypotension
c. syncope
d. hives
B
A severe reaction is also known as __
vasovagal
The moderate reaction is also known as ___
anaphylactic reaction
Which of the 3 categories of systemic rxns is the most common
MILD
Uticaria is considered ____ reaction
MILD
Syncope (or ___) is considered ____ reaction
fainting - MILD
Tachycardia is _____ reaction
Bradycardia is _____ reaction
Moderate
Severe
Angioedema is ____ reaction
Moderate
what is angioedema
swelling of soft tissue
Convulsion, LUC are ____ reaction
Severe
Respiratory arrest is _____ reaction
severe
What is the cause of mild reaction like nausea or syncope
Anxiety
normal excretion of contrast is _____ within ___
100% - 24hrs
Reactions can be delayed up to ____
48hours
all life-threatening events occur within the first ____ after injection
20 min
Kidneys lies in the ____ space
retroperitoneal
Which kidney is higher than other? Why
LEFT because of the liver on the right side
Location of adrenal gland
superior & medial to each kidney
Location of kidney
between iliac crest and xiphoid process (T11-L3)
which structure connect kidney to urinary bladder
ureters
Urine is eliminated from the body through ___
urethra
Kidneys are in the most ___ part of the abdominal cavity
a. anterior
b. posterior
posterior
Normal obliquity of kidneys? due to what?
30
psoas muscles on two side
Ureters are anterior to which muscle group
psoas
Ureter starts from _____ to ____
renal pelvis
urinary bladder
Why stones are a problem with ureters
ureters’ normal size are 1mm-1cm whereas stones are bigger than that. Thus, it causes pain for patient
how do you position patient for the right kidney to be parallel to IR
30 LPO
What are the kidneys’ functions (5)
- urine production & elimination
- regulate water levels
- regulate acid-base
- regulate electrolytes
- remove nitrogenous waste
what are 3 things that kidneys regulate
water level
pH
electrolytes
Why nitrogenous waste must be removed?
remain in blood –> renal dysfunction
what are considered nitrogenous waste
urea & creatinine
Kidneys receive arterial blood from _____ through____
abdominal aorta - L/R renal arteries
____ _____ must be a large vessels to return blood from kidneys back to circulatory system (heart)
renal veins
What is directly connected to IVC to return blood to the heart
renal veins
Renal veins are directly connected to _____ to return blood to the ____ side of the heart
IVC - right
Renal veins are _____ (anterior/posterior) to renal arteries
anterior
What structure is located along medial border of each kidney that all of the renal veins & renal arteries go through ?
hilum
what kind of blood is supplied thru the kidneys
oxygenated
Route for blood supply through kidney & back to heart
abdominal aorta –> renal arteries –> kidneys –> renal veins –> IVC –> RT atrium –> RT ventricle –> lungs –> LT atrium –> LT ventricle.
what is stenosis
narrowing
Which macroscopic structures provide protection for kidneys
renal capsule
which macroscopic structures is a blood supply for kidneys
cortex
Give macroscopic structures of kidney from outer to inner
capsule –> cortex –> medulla (has renal pyramids) –> renal column
Medulla contains ___
renal pyramids
Cortex dips between pyramids to form _____
renal columns
Minor calyx converged from ____
renal papilla
what is renal papilla
opening of renal pyramids
minor calyx merge to form ____
major calyx
major calyx unite to form _____
renal pelvis
renal pelvis continues to form ___
ureter
Route of urine
nephron –> minor calyx –> major calyx –> renal pelvis –> ureter –> urinary bladder
what is the microscopic structure of the kidney
nephron
what is the function of nephron
urine production
how many nephron per kidney
1 million
Blood flows to the nephron through ____
afferent arterioles
Blood filtration happened at the ____ inside the _____
glomeruli - nephron
___ go through glomeruli then thru ____
waste - glomerular capsule