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Human Disease and Therapeutics > Test 1 > Flashcards

Test 1 Flashcards

1
Q

Give the action and receptor for both Symp. and Parasymp. for…iris radial muscle

A

Symp: contracts A1

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2
Q

Give the action and receptor for both Symp. and Parasymp. for…Iris circular muscle

A

Parasymp: Contract M

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3
Q

Give the action and receptor for both Symp. and Parasymp. for…Heart stuff

A

Symp: increases B1-B2
Para: decreases M

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4
Q

Give the action and receptor for both Symp. and Parasymp. for…Bladder wall

A

symp: Relaxes B2
Para: contracts M

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5
Q

Give the action and receptor for both Symp. and Parasymp. for…Skeletal muscle blood vessels

A

Symp: Relaxes B2

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6
Q

Give the action and receptor for both Symp. and Parasymp. for…GI tract walls

A

Symp: Relaxes A2, B2
Para: contracts M

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7
Q

Give the action and receptor for both Symp. and Parasymp. for…Sphincter of GI

A

Symp: contracts A1
Para: relax M2

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8
Q

Give the action and receptor for both Symp. and Parasymp. for…Uterus pregnancy

A

Contracts on both!

Alpha and M

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9
Q

Give the action and receptor for both Symp. and Parasymp. for…Penis

A

Symp: ejaculate A (Point and Shoot)
Para: erection M

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10
Q

Give the action and receptor for both Symp. and Parasymp. for…Metabolic (liver, kidney)

A

Only Sympathetic, with Alpha or beta2

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11
Q

What type of drug (receptor, action) and what does it do…..Bethanechol

A

Muscarinic agonist

Increase GI function

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12
Q

What type of drug (receptor, action) and what does it do…..Pilocarpine

A

M agonist
Glaucoma drug contracts iris to let fluid out
Xerostomia drug as well

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13
Q

What type of drug (receptor, action) and what does it do…..Cevimeline

A

M agonist

Xerostomia drug

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14
Q

What type of drug (receptor, action) and what does it do…..Atropine

A

M antagonist

Blocks Muscarinic receptors

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15
Q

What type of drug (receptor, action) and what does it do…..Scopalamine

A

M antagonist

Motion sickness drug

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16
Q

What type of drug (receptor, action) and what does it do…..Mecamylamine

A

N antagonist

Antihypertensive

17
Q

What type of drug (receptor, action) and what does it do…..Succinylcholine

A

N antagonist

makes the endplate open and unresponsive to more ACh

18
Q

What type of drug (receptor, action) and what does it do…..Tubocurare

A

N antagonist

paralyzing Arrow poison, competes with ACh

19
Q

What type of drug (receptor, action) and what does it do…..Physostigmine

A

Cholinesterase Inhibitors

used for glaucoma, antidote for atropine

20
Q

What type of drug (receptor, action) and what does it do…..Donepezil

A

Cholinesterase Inhibitor

Alzheimers

21
Q

What type of drug (receptor, action) and what does it do…..Sarin

A

Cholinesterase inhibitors

irreversible nerve gas, muscle twitches

22
Q

What type of drug (receptor, action) and what does it do…..Phenylephrine

A

A1 agonist

decongestant, vasocontrictor, decreased heart rate

23
Q

What type of drug (receptor, action) and what does it do…..Prazosin

A

A1 antagonist

A1 blocker

24
Q

What type of drug (receptor, action) and what does it do…..Clonidine

A 
A2 agonist (neg feedback on EPI)
decreases blood pressure (bradychardia),
25
Q

What type of drug (receptor, action) and what does it do…..Guanfacine

A 
A2 agonist (neg feedback on EPI)
decreases blood pressure
26
Q

What type of drug (receptor, action) and what does it do…..Isoproteronol

A

B1 agonist

increases heart performance

27
Q

What type of drug (receptor, action) and what does it do…..Olol

A 
B1 antagonist
B blocker (decreases blood pressure)
28
Q

What type of drug (receptor, action) and what does it do…..Albuterol,

A

B2 agonist

Bronchodilator

29
Q

What type of drug (receptor, action) and what does it do…..Botulinim toxin

A

N antagonist

blocks release of ACh, relaxes muscles.

30
Q

What type of drug (receptor, action) and what does it do….. Terbutaline

A

B2 agonist

Bronchodilator

31
Q

What does Epi do to the body?

A

Increases heart rate, bronchodilator, decrease aqueous humor, relaxes bladder.

32
Q

What does dopamine treat?

A

shock and heart failure

33
Q

What does ephedrine do?

A

Stimulates release of NE (and everything that goes along with that)

34
Q

What does Amphetimines do?

A

increases the backwards release of DA through the DA transporter

35
Q

What does cocaine and methylphenidate do?

A

blocks DA reuptake through the transporter

36
Q

What does phenoxybenzamine, and phentolamine do?

A

decreases TPR and blood pressure (which then increases HR by baroreceptor)
side effect: hypotension

37
Q

If you get dry mouth, constipation, blurred vision, sedation, urinary retention what should you think?

A

Anti-cholinergic

Human Disease and Therapeutics (5 decks)

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