Test 1 Flashcards
Give the action and receptor for both Symp. and Parasymp. for…iris radial muscle
Symp: contracts A1
Give the action and receptor for both Symp. and Parasymp. for…Iris circular muscle
Parasymp: Contract M
Give the action and receptor for both Symp. and Parasymp. for…Heart stuff
Symp: increases B1-B2
Para: decreases M
Give the action and receptor for both Symp. and Parasymp. for…Bladder wall
symp: Relaxes B2
Para: contracts M
Give the action and receptor for both Symp. and Parasymp. for…Skeletal muscle blood vessels
Symp: Relaxes B2
Give the action and receptor for both Symp. and Parasymp. for…GI tract walls
Symp: Relaxes A2, B2
Para: contracts M
Give the action and receptor for both Symp. and Parasymp. for…Sphincter of GI
Symp: contracts A1
Para: relax M2
Give the action and receptor for both Symp. and Parasymp. for…Uterus pregnancy
Contracts on both!
Alpha and M
Give the action and receptor for both Symp. and Parasymp. for…Penis
Symp: ejaculate A (Point and Shoot)
Para: erection M
Give the action and receptor for both Symp. and Parasymp. for…Metabolic (liver, kidney)
Only Sympathetic, with Alpha or beta2
What type of drug (receptor, action) and what does it do…..Bethanechol
Muscarinic agonist
Increase GI function
What type of drug (receptor, action) and what does it do…..Pilocarpine
M agonist
Glaucoma drug contracts iris to let fluid out
Xerostomia drug as well
What type of drug (receptor, action) and what does it do…..Cevimeline
M agonist
Xerostomia drug
What type of drug (receptor, action) and what does it do…..Atropine
M antagonist
Blocks Muscarinic receptors
What type of drug (receptor, action) and what does it do…..Scopalamine
M antagonist
Motion sickness drug
What type of drug (receptor, action) and what does it do…..Mecamylamine
N antagonist
Antihypertensive
What type of drug (receptor, action) and what does it do…..Succinylcholine
N antagonist
makes the endplate open and unresponsive to more ACh
What type of drug (receptor, action) and what does it do…..Tubocurare
N antagonist
paralyzing Arrow poison, competes with ACh
What type of drug (receptor, action) and what does it do…..Physostigmine
Cholinesterase Inhibitors
used for glaucoma, antidote for atropine
What type of drug (receptor, action) and what does it do…..Donepezil
Cholinesterase Inhibitor
Alzheimers
What type of drug (receptor, action) and what does it do…..Sarin
Cholinesterase inhibitors
irreversible nerve gas, muscle twitches
What type of drug (receptor, action) and what does it do…..Phenylephrine
A1 agonist
decongestant, vasocontrictor, decreased heart rate
What type of drug (receptor, action) and what does it do…..Prazosin
A1 antagonist
A1 blocker
What type of drug (receptor, action) and what does it do…..Clonidine
A2 agonist (neg feedback on EPI) decreases blood pressure (bradychardia),
What type of drug (receptor, action) and what does it do…..Guanfacine
A2 agonist (neg feedback on EPI) decreases blood pressure
What type of drug (receptor, action) and what does it do…..Isoproteronol
B1 agonist
increases heart performance
What type of drug (receptor, action) and what does it do…..Olol
B1 antagonist B blocker (decreases blood pressure)
What type of drug (receptor, action) and what does it do…..Albuterol,
B2 agonist
Bronchodilator
What type of drug (receptor, action) and what does it do…..Botulinim toxin
N antagonist
blocks release of ACh, relaxes muscles.
What type of drug (receptor, action) and what does it do….. Terbutaline
B2 agonist
Bronchodilator
What does Epi do to the body?
Increases heart rate, bronchodilator, decrease aqueous humor, relaxes bladder.
What does dopamine treat?
shock and heart failure
What does ephedrine do?
Stimulates release of NE (and everything that goes along with that)
What does Amphetimines do?
increases the backwards release of DA through the DA transporter
What does cocaine and methylphenidate do?
blocks DA reuptake through the transporter
What does phenoxybenzamine, and phentolamine do?
decreases TPR and blood pressure (which then increases HR by baroreceptor)
side effect: hypotension
If you get dry mouth, constipation, blurred vision, sedation, urinary retention what should you think?
Anti-cholinergic
