Terms/Definitions- Connective Tissue Flashcards
Areolar connective tissue
Function: wraps and cushions organs
Location: widely distributed under epithelia of body
Dense irregular connective tissue
Function: able to withstand tension exerted in many directions; provides structural strength
Location: fibrous capsules of organs and joints; dermis of the skin; submucosa of digestive tract
Mesenchymal tissue
Function: gives rise to all other connective tissue types
Location: primarily in embryo
Elastic connective tissue
Function: allows recoil of tissue following stretching; maintains pulsatile flow of blood through arteries; aids passive recoil of lungs following inspiration
Location: walls of large arteries; within certain ligaments associated with vertebral column, within the walls of the bronchial tubes
Reticular connective fibers
Function: fibers form a soft internal skeleton that supports other cell types, including white blood cells, mast cells, and macrophages
Location: lymphoid organs (lymph nodes, bone marrow, spleen)
Hyaline cartilage
Function: supports and reinforces; has resilient cushioning properties; resists compressive stress
Location: forms most of the embryonic skeleton; covers the ends of long bones in joint cavities; forms the costal cartilages of the ribs, cartilages of the nose, trachea, and larynx.
Adipose tissue
Function: provides reserve fuel; insulates against heat loss; supports and protects organs
Location: under skin, around kidneys and eyeballs, within abdomen, in breasts.
Extracellular matrix
consists of fibers and ground substance
Collagen
most abundant protein of the body; thick, tough, resist stretch yet flexible; ex.- tendons, ligaments, dermis
Ground substance
material found between cells; consist of 3 classes of large molecules; glycosaminoglycans (GAGs)- polysaccharides that attract sodium and water, proteoglycan-thick gel/slows spread of pathogens, cell adhesive glycoproteins- allow themselves to bind to matrix elements
Fibroblasts
produce collagen, found in every tissue, allow production of fibrous tissue (which is used for healing); produces ground substance; reactive tissue
Pericytes
protect blood vessels and control permeability
Myofibroblasts
halfway between a muscle cell and fibroblast; most important in mammary cancer
Melanocytes
brown to gray staining cells on H&E staining; pigmentation of skin
Adipocytes
fat cells, nuclei difficult to see
Fibrocartilage
supportive connective tissue with rubbery matrix; chondroblasts produce matrix, surround and become chondrocytes, no blood vessels
Osteoblasts
lay down new bone
Osteoclasts
break down bone
Osteocytes
normal cells of the bones; once they are embedded; work to maintain the bone
Cortical bone
outside layer of bone; hard; haversian canals present; found in body of long bones; has a large blood supply
Cancellous
spongy material
Intramembranous ossification
bone formation without needing cartilage (flat bones)
Endochondral ossification
growth plates, series of steps of growth (long bones)
Chondroblasts
associated with developing cartilage; chondroblasts inside of lacuna are called chondrocytes