Terms Flashcards

1
Q

Physiology

A

science of the function of living systems

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2
Q

Organism

A

body made up of organs, organelles, or other parts that work together to carry on the various processes of life

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3
Q

Endocrinology

A

branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions called hormones, the integration of developmental events such as proliferation, growth and differentiation (including histogenesis and organogenesis) and the coordination of metabolism, respiration, excretion, movement, reproduction, and sensory perception dependent on chemical cues, substances synthesized and secreted by specialized cells

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4
Q

Parenchyma

A

functional tissue of an organ

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5
Q

Stroma

A

the connective tissue or framework of an organ; contains blood vessels, nerves

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6
Q

Capsule

A

surrounds gland

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7
Q

Trabeculae (septa)

A

divide glands into lobes or lobules

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8
Q

Endocrine vs. Nervous system

A

anatomically discontinuous but otherwise similar; both are major communication systems, integrate stimuli and responses to changes in external and internal environment, both are crucial to coordinated functions of highly differentiated cells, tissues, and organs

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9
Q

Principal functions of the endocrine system

A

maintains homeostasis; integration and regulation of growth, metabolism and development; control, maintenance and instigation of sexual reproduction, including gametogenesis, fertilization, fetal growth and development and nourishment of the newborn

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10
Q

Endocrine secretion

A

secreted into blood; binds distant target cells

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11
Q

Paracrine secretion

A

acts locally by diffusing from its source to target cells in the neighborhood

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12
Q

Autocrine secretion

A

acts on same cell that produced it

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13
Q

General principles of endocrine glands

A

ductless; highly vascular; functional secretory cells are usually epithelial

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14
Q

Types of endocrine organ arrangements

A
Discrete glands (thyroid)
Endocrine components of other organs (pancreas, gonads, ovaries, testis)
Scattered cells throughout other organs (C cells in thyroid)
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15
Q

Classes of hormones

A

Steroids, protein/peptide hormones, amino acid analogues and derivatives

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16
Q

Steroids

A

originate from cholesterol precursor
organs- ovaries, testis, adrenal cortex
specific hormones- mineralcorticoids, glucocorticoids, testosterone and estradiol
made- on demand, not stored; steroid producing cells have high levels of SER, Golgi

17
Q

Protein/peptide hormones

A

organs- anterior pituitary, thyroid, parathyroid, pancreas
specific hormones- insulin, prolactin, parathormone
protein-hormone producing cells have high levels of RER

18
Q

Amino acid analogues and derivatives

A

organs- thyroid and adrenal medulla
specific hormones- thyroxine, norepinephrine, epinephrine (catecholamines)
stored in granules

19
Q

Types of control mechanisms

A

External stimuli (cold, light, etc); Internal stimuli (blood sugar, hormonal signals); feedback loops

20
Q

Types of Hormone receptors

A

membrane receptors, cytoplasmic/nuclear receptors

21
Q

Intracellular receptors (cytoplasmic/nuclear)

A

characteristic of steroid/thyroid hormones
diffuse through plasma membrane
bind to receptor; receptor-hormone complex binds specific DNA sequences
directly alters gene expression
new mRNA and proteins made, new proteins change cell function

22
Q

Membrane receptors

A

used by hormones that cannot diffuse through plasma membrane (amines, peptides, proteins)
does not directly alter gene expression
G proteins in cell membrane are activated
1st messenger is hormone, 2nd messenger may be cAMP, cGMP, Ca++

23
Q

Lumen

A

inner open space or cavity of a tubular organ