Terbutaline (Brethine, Bricanyl)

Question 1

Classification

Answer 1

Sympathetic/adrenergic agonist, synthetic sympathomimetic

Question 2

Mechanism of Action

Answer 2

• Immediate bronchodilation with minimal cardiac side effects
• Stimulates the beta2 adrenergic receptors
• Produces relaxation of bronchial smooth muscles and bronchodilation

Question 3

Indications

Answer 3

• Bronchial asthma, reversible bronchospasm associated with chronic bronchitis and emphysema

Question 4

Contraindications

Answer 4

• Hypersensitivity
• Significant tachycardia, especially those caused by possible digitalis toxicity

Question 5

Adverse Effects

Answer 5

• Palpitations, anxiety, dizziness, headache, nervousness, tremors, HTN, arrythmias, chest pain, nausea, vomiting

Question 6

Administration

Answer 6

• 0.25 mg subQ or IM every 20 minutes for 3 doses

Question 7

Special Considerations

Answer 7

• ​Monitor vitals signs, caution in elderly patients with cardiovascular disease or HTN
• Beta blockers may blunt the effects of terbutaline