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2B1: imm voorbereiding > tentamen 3 > Flashcards

tentamen 3 Flashcards

1
Q

lokale effecten van inflammatoire cytokines

A
  • verhoogde vaatpermeabiliteit
  • activatie leukocyten
  • secretie cytokinen door T-cellen
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2
Q

systemische effecten cytokinen

A
  • koorts
  • productie eiwitten nodig voor acute fase ontsteking
  • productie leukocyten
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3
Q

Gram-positieve bacteriën

A

dikke peptidogylcaan laag > afgebroken door lysozym
Staphylococcus aureus
streptococcus pneumaniae

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4
Q

gram-negatieve bacteriën

A

dunne peptidoglycaan laag, omgeven door buitenmembraan met lipopolysacchariden
escherechia coli
salmonella spp

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5
Q

gp120

A

uitsteeksel op HIV dat ervoor zorgt dat virus kan hechten aan gastheercel

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6
Q

X4-trope virussen

A

HIV virussen, die naast CD4 receptor, alleen CXCR4 co-receptor kunnen gebruiken om CD4+ cellen te infecteren
infecteren vooral lymfocyten

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7
Q

levende, verzwakte virussen

A

mazelen
bof

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8
Q

geïnactiveerde (dode) virussen

A

griep
polio
hepatitis A

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9
Q

recombinatie subunit vaccins

A

hepatitis B
HPV

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10
Q

outercortex lymfeklier

A

follikels
FDC
randsinus
trabekelsinus

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11
Q

paracortex lymfeklier

A

HEV voor aanleveren nieuwe leukocyten
(trabekel)sinussen

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12
Q

medulla lymfeklier

A

mergsinussen
mergstrengen

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13
Q

IgA1

A

in serum
korte hinge region
gevoelig voor proteolyse

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14
Q

IgA2

A

in externe secreten
langere hinge region
minder gevoelig voor proteolyse

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15
Q

route T-lymfocyten thymus

A

innercortex > oudercortex > medulla

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16
Q

positieve selectie T-lymfocyten

A

in cortex
door cTECs
voor herkennen HLA

17
Q

negatieve selectie T-lymfocyten

A

in medulla
eigen peptiden gepresenteerd door mTECs en DC
selectie tegen TCR met te hoge affiniteit tegen eigen peptiden

18
Q

aantonen m. tuberculosis

A

quantiferon test
ELISPOT
Mantoux test

19
Q

risicofactor mazelen

A

incomplete vaccinatiestatus

20
Q

risicofactor HIV

A

(sub)acute of chronische infectie

21
Q

risicofactor EBV

A

immuungecompromiteerd

22
Q

risicofactor arbovirus

A

reishistorie

2B1: imm voorbereiding (9 decks)

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