TDM Flashcards
1
Q
phenytoin target levels
A
10-20mg/l
2
Q
dose of phenytoin
A
LD: 15-20mg/kg in 3 doses
MD: 4-6mg/kg in 2-4 divided doses
3
Q
when to draw the levels of phenytoin
A
IV 2h after dose
PO 24h after
trough: 1h before morn dose
maintenance every 7d
4
Q
valproate target levels
A
50-100mg/L
5
Q
doses of valproate
A
LD: 20-30mg/kg
MD: 10-15mg/kg
6
Q
when to draw valproate doses
A
2-3d after LD , 3-5d after MD
7
Q
carbamazepine target levels
A
4-12mg/L
8
Q
dose for carbamazepine
A
100-200mg/d
9
Q
when to draw trough for carbamazepine
A
2weeks
10
Q
phenobarbital levels
A
10-30mg/L
11
Q
dose for phenobarbital
A
LD: 15-20mg/kg
MD: 10mg/h IV, 2mg/kg/d PO
12
Q
when to draw levels for phenobartial
A
2-3h post infusion then 3-4d
if MD 2wks
