parkinson drugs Flashcards
levodopa side effects
nausea, dizziness, OH, headache, hallucination, dyskinesia, constipation
levodopa precaution
CVS, endocrine, glaucoma, pud, resp depression
levodopa monitoring parameters
sx of parkinson diseases, mental status, cardiac function, IOP,
entacapone SE
nausea, dizziness, OH, abdominal pain, urine discolouration, hyperkinesia, diarrhoea
entacapone precaution
- Patients with orthostatic hypotension
- Cumulative side effects
- CVS diseases such as MI, arrhythmias
entacapone monitoring parameters
sx parkinsons, LFT, BP, weight loss, dermatologic examinations
tolcapone
- Orthostatic hypotension
- Drowsiness
Nausea - Hallucination
- Dyskinesia
- Muscle cramps
- Dirrhoea (usually after 6 to 12 weeks)
Higher prevelance of side effects than entacapone
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bromocriptine SE
dizziness, headache, OH, constipation, asthenia (weakness)
bromocriptine precaution
cardiac valvular fibrosis, cns depression, hallucination, impulse control, PUD
bromocriptine monitoring parameters
- BP and HR (signs of orthostatic vitals)
- Hepatic function
- Rena function
4, CVS dunction - Visual fields