DM drugs

Question 1

goacarbose

Answer 1

initial 50mg TDS
max 100-200mg TDS
crlcl<25: not required

Question 2

acarbose SE

Answer 2

GI flactulence, diarrhoea, abdominal pain

Question 3

metformin

Answer 3

IR 500-850mgTDS max 1000mg
XR: 500mg OD max 2g OD
eGFr<30 CI

Question 4

metformin SE

Answer 4

GI nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, metallic taste

Question 5

linagliptin

Answer 5

5mg OD

Question 6

sitagliptin

Answer 6

100mg OD
eGFR 30-45: 50mg OD
eGFR <30: 25mg OD

Question 7

DPP4I SE

Answer 7

nasopharyngitis, URTI, cough, headache, dizziness

Question 8

dulaglutide

Answer 8

SC 0.75mg 1x/wk, 1.5mg 1x/wk

Question 9

liraglutide

Answer 9

SC 0.6mg OD -1.8mg OD

Question 10

semaglutide

Answer 10

SC 0.25 1x/wk max 1mg 1x/wk
PO 3mg OD-14mg OD

Question 11

GLP-1 SE

Answer 11

GI, headache, nasopharyngitis, injection site rxn

Question 12

canagliflozin

Answer 12

100mg OD
300mg OD
eGFR 30-59 max 100mg OD
<30: not recommended

Question 13

dapagliflozin

Answer 13

10mg OD
<25 not recommended

Question 14

empagliflozin

Answer 14

10mg OD
25mg OD
<20: not recommended

Question 15

SGLT2i SE

Answer 15

genital mycotic infections, urinary tract infections, polyuria

Question 16

glicazide

Answer 16

IR 80mg OD-160mg BD
MR 30-120mg OD

Question 17

glipizide

Answer 17

2.5-5mg OD
max 20mg in 2 doses