TBL 5B General Embryology Flashcards
Fertilisation usually occurs at the _____ of the uterine tube.
ampulla (Widest part of the fallopian tube)
The lateral end of the Fallopian tube has finger-like projections known as _____. These projections help to bring the oocyte into the fallopian tube.
fimbria
If the oocyte is not fertilised in the ampulla, it will pass along the fallopian tube into the _______, where it degenerates.
uterine cavity
The plasma membrane of the oocyte is surrounded by a glycoprotein coat known as ___________.
zona pellucida
The glycoprotein coat surrounding the plasma membrane of the oocyte, known as zona pellucia, is in turn surrounded by layers of follicular cells known as ________.
corona radiata
Fertilisation occurs in 3 phases. Rearrange the following.
A) Penetrate zona pellucida
B) Penetrate corona radiata
C) Fusion of plasma membranes of oocyte and sperm.
- Penetrate corona radiata
- Penetrate zona pellucida
- Fusion of plasma membranes
The head of the sperm is covered with ______, which releases hydrolytic enzymes to dissolve the zona pellucida around the egg.
acrosome
During fusion of plasma membranes of the egg and sperm, the ______ and ______ of the sperm remains behind.
plasma membrane and mitochondria
When the first sperm touches the oocyte, the plasma membrane of the oocyte depolarises. ___________ will release enzymes to cause the zona pellucida to become impenetrable to other sperms. These prevent _______.
Cortical granules will release enzymes; preventing polyspermy
Compaction occurs after the __-cell stage, where the blastomeres change their shape to tightly align themselves against each other by tight junctions to form a compact ball of cells.
8-cell
The 16-cell stage embryo is known as ______.
morula (mulberry)
Shortly after the morula (___-cell stage) enters the uterine cavity, the fluid from the uterine cavity passes through the zona pellucida to form the __________ in the morula.
blastocyst cavity
At the 16-cell stage, the blastomeres are separated into 2 parts - inner cell mass (known as _________) and outer cell mass known as __________.
ICM - embryoblasts
outer cell mass - trophoblast
5 days after fertilisation, the blastocyst hatches out of the ________, and is ready for implantation.
zona pellucida
Implantation refers to the blastocyst attaching itself to the ___________.
endometrium epithelium
Once implantation to the endometrium occurs, the trophoblast differentiates into 2 layers - ______ and _______.
synctiotrophoblast (outermost layer) and cytotrophoblast (inner layer)
The ________ of the blastocyst has finger-like projections which penetrate the endometrium of the uterus to implant the blastocyst.
synctiotrophoblast
________ pregnancy refers to blastocyst implant in abnormal locations outside the uterus.
Ectopic pregnancy
In the 2nd week of development, the embryoblast differentiates into 2 layers - _____ and _____. This is known as the formation of bilaminar germ disc from the embryoblast.
Epiblast (3rd) and hypoblast (4th)