TBL 10 Flashcards by leslie espindola

Q

Antibody-mediated disorders (type II)

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Immediate hypersensitivity (type I)

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Immune complex-mediated disorders (type III)

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Cell-mediated immune disorders (type IV)

A

CD4 is the major cell

48 -72 hours after exposure

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

major players of type 1?

A

mast cell, eosinophil, basophil, igE

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

first vs subsequent exposure to antigen in type 1

A

2, receptors are already found to mast cell, so crosslinking occurs

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

where are mast cells found ?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

which portion of the Fc epsilon receptor I has carried the binding site for IgE? and which one is for signaling ?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

what are the 3 responses of mast cells to secondary exposure in type 1?

A

CROSSLINKING OCCURS

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

PROPERTIES OF MAST CELLS, BASOPHILS, AND EOSINOPHILS

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

response created with parasites

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

what determines if Th0 will become a Th2?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

genes invloved in type 1

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

IgE-MEDIATED ALLERGIC REACTIONS CONSIST OF AN IMMEDIATE
RESPONSE FOLLOWED BY A LATE-PHASE RESPONSE

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Mediators Released During Immediate and Late Phase

A

Immediate mediators: histamine

late response:
cytokines, chemokines, lipid mediators

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

histamine effects

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ALLERGIC RHINITIS/HAY FEVER

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

what are the mechanisms of antibody meadiated diseases?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

what are the mechanisms of antibody meadiated diseases?

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Type II clinical examples?

drugs that cause these reactions

A

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

if mistch of blood happens, what will happen?

A

Q

ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
(ADCC), what cells are able to do this?

and what types of molecules do they use?

A

MENN are toxic

Q

when to give RhoGAM

A

direct coombs test is used to test which type of hypersensitive and when is it used?

Type II

indirect combs test

ANTIBODY-MEDIATED/ TYPE II HYPERSENSITIVITY-MEDIATED AUTOIMMUNE DISEASES

Drug-induced Anemia or Thrombocytopenia Most common:______________ type_____reaction how do we remove it from the system?

Penicillin-Induced Type II Response

what is rheumatic fever?

why does rheumatic fever occur and what other tissues are involved?

symptoms to rheumatic fever?

how to diagnose rheumatic fever?

type III antigens and what kind of problems will they cause

type III categories of immune complex diseases?

mechanism of poststreptococcal glomerulonephritis ?

TYPE III: IMMUNE COMPLEX-MEDIATED HYPERSENSITIVITY dieseases

Polyarteritis nodosa (PAN) is a rare type of vasculitis that causes inflammation of the medium-sized arteries.

when will the body not be able to clear the type III complexes

explain mechanism of the basis of immune reaction of type III?

serum sickness disease is an example of ?? how does it work? symptoms associated with it

type III it is systemic

route of antigen entering body in type III and resulting disease?

arthus reaction mechanism? and what type of hypersensitivity is it? what kind of cell binds to AB and which recpetor? does not happen immediately

type III, dont confuse with one, It is mast cell, but Fc Gamma receptors bound to IgG does not happen immediately (within minutes) notice TIME

T CELL-MEDIATED HYPERSENSITIVITY diseases Delayed Type IV Hypersensitivity (DTH)

SYSTEMIC ANAPHYLAXIS common causes?

EARLY AND LATE PHASE RESPONSE IN ALLERGIC ASTHMA

Penicillin-Induced Systemic Anaphylaxis (type I)

Penicillin-Induced Systemic Anaphylaxis mechanism

HYPERSENSITIVITY TYPE IV characteristics

requirement for T CELL-MEDIATED DELAYED HYPERSENSITIVITY

DELAYED TYPE HYPERSENSITIVITY (DTH) and examples. Primary and secondary mediators

Delayed-Type Hypersensitivity mechanism

INTRACELLULAR PATHOGENS & CONTACT ANTIGENS THAT INDUCE DTH (DELAYED TYPE HYPERSENSITIVITY) The Type IV response is designed to eliminate parasites and ________ Problems arise when the response is prolonged as a result of failure to eliminate the pathogen.

contact dermatitis