TB Drugs

Question 1

MDR-TB is resistant too what drugs?

Answer 1

Isoniazid (INH) & Rifampin

Question 2

XDR-TB is of special concern for patients who have

Answer 2

AIDs or are otherwise immunocompromised

Question 3

Vaccine injection derived from an inactivated strain of M. Bovis; used to vaccinate yourg children; does not prevent infection

Answer 3

Bacille Calmette-Guerin (BCG)

Question 4

Diagnostic injection given Intradermally to detect exposure to TB

Answer 4

Purified protein derivative (PPD) (Mantoux)

Question 5

Major effect of drug therapy for TB

Answer 5

reduction of cough-reduction of infectious pt

Question 6

Successful treatment of TB timeline:

Answer 6

at least 6 months and sometimes for as long as 12 months

Question 7

Effectiveness of Anti TB therapy depends on:

Answer 7

type of infection
adequate dosing
sufficient duration of treatment
adherence to drug regimen
Selection of an effective drug combo

Question 8

Perform what testing for patients who are receiving Rifampin & INH?

Answer 8

Liver function studies

Question 9

Rifampin causes what to become ineffective?

Answer 9

oral contraceptives

Question 10

Rifampin causes what in urine; stool; saliva; sweat

Answer 10

Reddish orange color

Question 11

What drug may need to combat neurologic adverse effects associated with INH therapy?

Answer 11

Pyridoxine

Question 12

Food & TB therapy?

Answer 12

yes, even though recommendations are to take them 1 hour before or 2 hrs after meals

Question 13

Bedaquiline (Sirturo) Adverse effects

Answer 13

QT prolongation; headache; chest p!

Alcohol interaction

Question 14

Ethambutol contraindications:

Answer 14

peds patients under 13

Question 15

PZA & contrainidcations

Answer 15

gout, hepatic disease

Question 16

INH watch for

Answer 16

“slow acetylators”

Question 17

first bacteriostatic drug

Answer 17

Ethambuotol

Question 18

Aminoglycoside antibiotic

Answer 18

Streptomycin

Question 19

Bedaquiline you take

Answer 19

with food

Long OT

Question 20

Liver toxicity s/s

Answer 20

dark urine
Jaundice
Fatigue

Question 21

INH adverse effects

Answer 21

hepatoxicity

peripheral neuropathy

Question 22

What vitamin with INH?

Answer 22

B