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Microbiology > TB drugs > Flashcards

TB drugs Flashcards

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Biology 101 flashcards
1
Q

Metabolized in the liver by N acetyltransferase(NAT)

Excreted as hydrszone metabolites and unchanged in urine

A

Isoniazid

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2
Q

DOC to prevent peripheral neuropathies in isoniazid

A

B6. Pyridoxine

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3
Q

inhibits RNA polymerase

A

Rifampicin

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4
Q

can treat leprosy and meningococcal carriage

H.influenza prophylaxis in children

A

Rifampicin

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5
Q

inhibits ARABINOSYL transferase

dose related toxicity

A

Ethambutol

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6
Q

Toxic dose of ethambutol and effects

A

> 25 mg/kg

retrobulbar neuritis; red green color blindness

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7
Q

Hepatotoxicity

Hyperurecemia

A

PZA

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8
Q

30s aminoglycoside

A

Streptomycin

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9
Q

Ototoxicity
Nephrotoxicity
Dose related SE

A

Streptomycin

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10
Q

3 drugs OK for pregnancy

A

INH
EMB
RIF

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11
Q

causes congenital deafness

A

streptomycin

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Microbiology (22 decks)

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