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Microbiology > Chillout 2 > Flashcards

Chillout 2 Flashcards

1
Q

Medussa head

locks of matted hair

A

Bacillus Anthracis

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2
Q

Pathogenic factors of anthrax

A

Lethal and Edema - kills

Protective antigen - mediates entry

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3
Q

What type of anthrax that kills?

A

Pulmonary anthrax

“woolsorter’s disease”

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4
Q

Hemorrhagic pneumonia..
death in 1 to 3 days.
Spore inhilation

A

Pulmonary anthrax

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5
Q

MC type of anthrax

A

Cutaneous(95%)

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6
Q

tx for anthrax

A

PEN G
erythromycin
vaccine

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7
Q

Malignant postule is aka

A

Black eschar

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8
Q

Two toxins of Bacillus cereus

A

Enetic - fried rice

Diarrheal - meat dishes and sauces

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9
Q

Bacillus anthracolis is made up of….

A

Poly D Glutamate

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10
Q

What is life-threatening pneumoniancharacterized by mediastinal hemorrage lymphadenitis?

A

Woolsorter’s disease or Pulmonary Anthrax

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11
Q

Warm food poisoning

A

B. cereus

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12
Q

Malignant pustules and CENTRAL necrosis or eschar formation with painful regional lymphadenopathy

A

Cutaneous anthrax

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13
Q

Slow growing obligate aorobe

A

Slipping and Snapping forms

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14
Q

(+) niacin

Catapase (-) @ 68 degress

A

MTB

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15
Q

Serpentine growth

A

MTB

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16
Q

What causes the serpentine growth in vitro?

also responsible for virulence

A

Cord Factor - Trehalose Dimycolate

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17
Q

how many weeks does MTB need to be positive for culture?

A

6 weels

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18
Q

responsible for caseous necrosis

A

phosphatides

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19
Q

Granuloma with typical Langhan’s giant cells, epithelioid cells and fibrosis

A

Classic tuhular lesion of MTB

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20
Q

Conditions with

apical infiltrates and perihilar cavitations

A

Wegener’s granulomatosis
Sarcoidosis
MTB

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21
Q

Provides a definitive dx for active TB

A

Direct sputum mocroscopy

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22
Q

Bone TB in children and in adult location

A

Upper thoracic: children

Lower thoracic/upper lumbar infiltrates: adults

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23
Q

Skip lesions and cobblestone appearance conditions

A

TB

Crohn’s

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24
Q

Difference in TB and Crohns

A

Granuloma in TB

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25
Q

Most common initial presentation of PTB

A

wt loss

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26
Q

most common extrapulmonary sitenof TB

A

LN

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27
Q

Best initial test for TB

A

CXR

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28
Q

Positive PPD is defined as

A

Induration equal or greater than 10mm after 4i8 to 72 hours after injection

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29
Q

Positive PPD test in HIV px

A

5mm

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30
Q

Natural Resistance Assoc Macrophage protein (NRAM) genetic protein
BEG gene

A

Mycobacrerium avium intracellulare

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31
Q

Anti TB drugs should have these 3 properties

A

bactericidal
sterilizing
ability to prevent resistance

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32
Q

First line TB drugs

A 
Isoniazid
Rifampin
Ethambutol 
Pyrazinamide
Streptomycun
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33
Q

Second line drugs for TB

A

Quonolones

Aminoglycosides

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34
Q

Hansens disease

A

Leprosy

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35
Q

Toxin of M. leprae

A

NONE

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36
Q

the only bacterium that invades peripheral nerves

A

M. leprae

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37
Q

M. leprae cell wall contains what?

A

phenolic glycolipid(PGL-1)

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38
Q

M.leprae like this types of temp and tissues

A

Cool skin and extremities

32C-34C

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39
Q

Packs of cigars in microscope

A

M. leprae

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40
Q

M.leprae skin test

41
Q

determines weather the leprosy is tuberculoid or lepromatous

A

Th lymphocyte response

42
Q

Incubation period of leprosy

A

2-40 years

generally 5-7yrs

43
Q

skin anesthesias
asymmetric enlargement of one or a few peripheral nerves
muscle atrophy

A

Tuberculoid leprosy (TT, BT)

44
Q

Type of leprosy
CD4 helper T predominates
positice lepromine
Absent or few in AFB

A

tuberculoid leprosy

45
Q

Type of leprosy

most unstable form
“punched out” or “swiss cheese” appearance

A

Borderline leprosy

46
Q

Type of leprosy

Aka anergic
Numerous in AFB
CD8 predominates
symmetric nerver enlargement
upper RT, anterior eye chamber and the testes
negstive lepromin test
A

Polar Lepromatous leprosy

47
Q

leprosy Tx

A

Dapsone
clofazimine
rifampin

48
Q

TB mening affects what part of the brain?

A

Brain stem

CN III VI VII

49
Q

Most serious complication of TB meningitis

A

Hydrocephalus

endarteritis

50
Q

CSF in TB meningitis shows

A

Spiderweb coagulum

51
Q

CSF in TB meningitis

A

High protein High leukocyte

Low glucose

52
Q

gold standard for TB meningitis

53
Q

Adjunctive Glucoccorticoid Therapy

A

Dexamethasone

54
Q

H. influenza virulence factore

A

IgA protease

55
Q

H. influenza agar

A

chocolate agar

56
Q

haEMOPhilus is

A

Epiglottis
meningitis
otitis media
pneumonia

57
Q

Capsulated Neiserria with negative beta lactamase production

A

N. meningitidis

58
Q

Green metallic stresks

59
Q

substance in E coli causing neonatal sepsis and meningitis

A

K1 capsule endotoxin

60
Q 
E. coli Serotype 0157
HUS
hamburgers
microangiopathic hemolytic anemia
renal failure
thrombocytopenia
61
Q

Gram (-) bacilli
raw eggs
poluted water

A

Salmonella

62
Q

Salmonella reservior

A

Galbladder

63
Q

test for S. typhi

A

Widal trest

typhidot

64
Q

Typhoid fever diseases

A

Dysentery
Ileitis
sickle cell anemia

65
Q

Specimens taken

A

1st week Blood
2nd Urine
3rd stool

Best specimen- hone marrow

66
Q

Rose spots

67
Q

“hyperplasia ofbthe Peyer’s patch

A

Typhoid ileitis

68
Q

DOC for typhoid

A

Ceftriaxone

Old school Choromycetin

69
Q

Meningitic oe typhoid dose for ceftriaxone

70
Q

Vibrio cholera 01-eltor toxin

A

Choleragen toxin

71
Q

Culture medium for V. cholera

A

thiosulfate citrate bile salt sucrose agar

72
Q

“rice water stool”

pea soup diarrhea

73
Q

Toxin Hemolysin
Gastroenteritis
Seafood/shelldish

A

V. parahemolyticus

74
Q

Vibrio + Cellulitis

A

V. vulnificus

75
Q

UTI and Kidney stones

76
Q

Swarming growth

77
Q

type of flagella in Proteus

A

Peritrichous flagella

78
Q

Enxyme produced by proteuse

A

Urease and

Phenylalanine deaminase + Fecl3 = green

79
Q

Proteus antigens that cross reacts with ricketsia

A

OX-19 OX-2 andn OX-K

80
Q

heterophile agglitination test for rickets proteus x reaction

A

Weil Felix reaction

81
Q

Staghorn calculi

82
Q

Gram neg rod
Oxidase +
non fermenting
Obligate aerobe

A

Pseudomonas

83
Q

Pigments in pseudomonas

A

pyocyanin

pyoverdin

84
Q

most common cause of gram negative nosocomial pneumonia and

mc in severe burn infections

A

Pseudomonas

85
Q

icthyma gangrenosum

A

hot tub folliculitis in pseudomonas infection

86
Q

Oral antihiotic with anti pseudomonal average

A

Ciprofloxacin

87
Q

Smallest free living bacteria

A

mycoplasma

88
Q

Eaton’s agar

A

mycoplasma

89
Q

Fried egg appearance on culture

A

mycoplasma

90
Q

McC cause of atypical pneumonia

Clinical findings not compatible with Xray

A

Mycoplasma pneumonia

91
Q

Cold agglutinin(+) causing anemia

A

Mycoplasma

92
Q

Bullous myringitis

A

vesicles in tympanic membrane in Mycoplasma

93
Q

Grame negative
Facultatice
Intracellular

94
Q

Stain in legionella

95
Q

Fever
hyponatremia
Confusion

A

legionaires dse

96
Q

Bat droppings

A

histoplasma

97
Q

tx for legionares dse

A

erythromycin

Macrolides

98
Q

Skinning of an infected animal
bitten by a dear fly
esting uncooked meat by a diseased animal

A

Francicella tularensis

99
Q

Most common form of Francicella tularensis

A

Ulceroglandular

Microbiology (22 decks)

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