Takayasu Arteritis Flashcards

1
Q

who gets it?

A

mainly before 50
perhaps 100x higher in East Asian countries
young women in 2nd and 3rd decades of life

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does it present?

A

early features are non-specific: low-grade fever, malaise, night sweats, weight loss, arthralgia, fatigue
claudicant symptoms in upper & lower limbs
if untreated – vascular stenosis & aneurysm can occur
o reduced pulses
o bruits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

how is it investigated?

A

CPR, PV/ESR elevated

MR angiography: detect thickened vessel walls and stenosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how is it managed?

A

prednisolone starting at 40-60mg gradually reduced

steroid sparing agents such as methotrexate and azathioprine may be added

How well did you know this?
1
Not at all
2
3
4
5
Perfectly