TABLET, PILLS, SUPPOSITORIES Flashcards
Are solid dosage forms usually prepared with the aid of suitable pharmaceutical excipients.
Tablet
varies in size, shape, weight, hardness, thickness, disintegration, depending upon the use and method of manufacturing.
Tablet
Add necessary bulk to a formulation to prepare tablets of the desired size
Diluent or Filler
Promotes adhesion of the particles of the formulation, allowing granulation to be prepared and maintaining the integrity of the final tablet.
Binders or Adhesives
Promote breakup of the tablets after administration to smaller particles for drug availability.
Disintegrant
Prevent material from sticking to the punches and dies.
Antiadherents
Enhance flow properties of the powder mixture.
Glidants
To reduce friction during compression.
Lubricants
2 types of Miscellaneous adjuncts.
Flavorants, Colorants
3 types of Coating
Sugar coated
Film coated
Enteric coated
refers to tablets having pieces broken out or chipped, usually around the edges.
Chipping
Cracked in the center
Cracking
It occurs when the upper segment of the tablet separates from the main portion of the tablet and comes off as a cap.
Capping
It is due to the same causes as capping except that the tablet splits and comes apart at the sides and is ejected in two parts.
Lamination
Molded tablet
Tablet triturates
small, usually cylindrical, molded, or compressed tablets containing small amounts of usually potent drugs mixed with a combination of sucrose and lactose or any suitable diluent.
Tablet triturates or Molded tablets
quickly disintegrate in the presence of moisture.
Table triturates or molded tablets
easily adjust the composition for any number of dosages.
Tablet triturates or molded tablets
their small size will limit their use to substances effective in small doses.
Tablet triturates or molded tablets
are generally prepared by mixing the active drug with lactose, dextrose, sucrose, mannitol, or some other appropriate diluent that can serve as the base.
Molded tablets
Molded tablets are generally prepared by mixing the active drug with ______, ______, ______, ______ or some other appropriate diluent that can serve as the base.
Lactose
Dextrose
Mannitol
Sucrose
This base must be readily water soluble and should not degrade during the tablet’s preparation.
Molded tablet