TABLET, PILLS, SUPPOSITORIES

Question 1

Are solid dosage forms usually prepared with the aid of suitable pharmaceutical excipients.

Answer 1

Tablet

Question 2

varies in size, shape, weight, hardness, thickness, disintegration, depending upon the use and method of manufacturing.

Answer 2

Tablet

Question 3

Add necessary bulk to a formulation to prepare tablets of the desired size

Answer 3

Diluent or Filler

Question 4

Promotes adhesion of the particles of the formulation, allowing granulation to be prepared and maintaining the integrity of the final tablet.

Answer 4

Binders or Adhesives

Question 5

Promote breakup of the tablets after administration to smaller particles for drug availability.

Answer 5

Disintegrant

Question 6

Prevent material from sticking to the punches and dies.

Answer 6

Antiadherents

Question 7

Enhance flow properties of the powder mixture.

Answer 7

Glidants

Question 8

To reduce friction during compression.

Answer 8

Lubricants

Question 9

2 types of Miscellaneous adjuncts.

Answer 9

Flavorants, Colorants

Question 10

3 types of Coating

Answer 10

Sugar coated
Film coated
Enteric coated

Question 11

refers to tablets having pieces broken out or chipped, usually around the edges.

Answer 11

Chipping

Question 12

Cracked in the center

Answer 12

Cracking

Question 13

It occurs when the upper segment of the tablet separates from the main portion of the tablet and comes off as a cap.

Answer 13

Capping

Question 14

It is due to the same causes as capping except that the tablet splits and comes apart at the sides and is ejected in two parts.

Answer 14

Lamination

Question 15

Molded tablet

Answer 15

Tablet triturates

Question 16

small, usually cylindrical, molded, or compressed tablets containing small amounts of usually potent drugs mixed with a combination of sucrose and lactose or any suitable diluent.

Answer 16

Tablet triturates or Molded tablets

Question 17

quickly disintegrate in the presence of moisture.

Answer 17

Table triturates or molded tablets

Question 18

easily adjust the composition for any number of dosages.

Answer 18

Tablet triturates or molded tablets

Question 19

their small size will limit their use to substances effective in small doses.

Answer 19

Tablet triturates or molded tablets

Question 20

are generally prepared by mixing the active drug with lactose, dextrose, sucrose, mannitol, or some other appropriate diluent that can serve as the base.

Answer 20

Molded tablets

Question 21

Molded tablets are generally prepared by mixing the active drug with ______, ______, ______, ______ or some other appropriate diluent that can serve as the base.

Answer 21

Lactose
Dextrose
Mannitol
Sucrose

Question 22

This base must be readily water soluble and should not degrade during the tablet’s preparation.

Answer 22

Molded tablet

Question 23

it is the preferred base but mannitol adds a pleasant, cooling sensation and additional sweetness in the mouth.

Answer 23

Lactose

Question 24

The base ordinarily used for molded tablet triturates is?

Answer 24

Lactose

Question 25

Lactose containing in what percent?

Answer 25

10-20% of sucrose

Question 26

Drugs that react chemically with sugars require special bases such as precipitate calcium carbonate, precipitated calcium phosphate, kaolin, or bentonite.

Answer 26

Lactose

Question 27

Drugs that react chemically with?

Answer 27

Sugars

Question 28

Give 1 advantage of lactose

Answer 28

Rapidly absorbed

Question 29

TABLET TRITURATES Synonym: Uses: Method of preparation: Appropriate container: Storage condition: Ingredients:

Answer 29

Molded tablets Tablet excipients (diluent) and sweetener Wide mouth bottle Machine molding Store at room temperature Lactose, 95% alcohol, API, Moistening Agent

Question 30

solid oral dosage form consist of one or more medicaments incorporated in a small, round, spherical or ovoid mass that are intended for oral administration.

Answer 30

Pills

Question 31

formerly the most extensively used oral dosage form, but they have been replaced largely by compressed tablets and capsules.

Answer 31

Pills

Question 32

easy to make and compact in quantity.

Answer 32

Pills

Question 33

masked bitter or unpleasant tastes and odors.

Answer 33

Pills

Question 34

stable for long periods and can be administered in this form if the dose is not too large.

Answer 34

Pills

Question 35

What are the 2 types of Pills

Answer 35

Compressed pills Dispensing pills

Question 36

This excipient formed a ______, very adhesive liquid that was usually prepared in advance of compounding the pills.

Answer 36

Colorless

Question 37

What are the 4 generic pill excipients?

Answer 37

Lactose Glycerin Powdered acacia Benzoic acid

Question 38

used as a preservative and might be omitted if only a small batch of pill mass was being compounded.

Answer 38

Benzoic acid

Question 39

What is the active ingredient of pills?

Answer 39

Benzoic acid

Question 40

gave mass the appropriate consistency of adhesiveness, firmness and plasticity.

Answer 40

Excipient

Question 41

Steps in making pills

Answer 41

Hand rolling Packaging Forming a mass and kneading using a mortar and pestle

Question 42

What are the 4 classes of pills

Answer 42

Parvules Boluses Granules Pills

Question 43

(small pills)-20mg and less potent substance with coloring agents

Answer 43

Parvules

Question 44

20 mg to 60mg it contains sugar

Answer 44

Granules

Question 45

60mg to 500mg comes in variety of sizes, shapes, coating and color

Answer 45

Pills

Question 46

(big pills) 700mg to 2000mg for veterinary use.

Answer 46

Boluses

Question 47

MAGNESIUM SULFATE PILLS Synonyms: Uses: Method of preparation: Appropriate container: Storage condition: Ingredients:

Answer 47

Epsom salt Saline laxative Hand molding Wide mouth Place it in tight container store at room temperature Magnesium sulfate, Hard soap, API, Purified water, Moistening agent

Question 48

Latin word of suppositories

Answer 48

Supponere

Question 49

What is supponere means?

Answer 49

To place under

Question 50

Solid dosage forms of various weights and shapes, usually medicated, intended for insertion into body orifices.

Answer 50

Suppositories

Question 51

What happen to the suppositories after you insert it?

Answer 51

Dissolve or melt

Question 52

prepared extemporaneously by incorporating the medicaments into the base and the molten mass is then poured at a suitable temperature into molds and allowed to cool until set.

Answer 52

Suppositories

Question 53

3 types of suppositories

Answer 53

Rectal, Vaginal, urethral suppositories

Question 54

What are the methods of preparation of suppositories?

Answer 54

Hand rolling Compression Fusion

Question 55

SUPPOSITORIES Synonyms: Latin name: Uses: Formulation:

Answer 55

Glycerol suppositories Suppositoria glycerini Laxative -glycerin, sodium carbonate, stearic acid, distilled water Melt molding