POWDERS, GRANULES, CAPSULE Flashcards
A pharmaceutical powder is a mixture of finely divided drugs from the comminution of chemicals in dry form.
Powders
• Flexibility of compounding
• Good chemical stability
• Rapid dispersion of ingredients because of the small particle size
Advantages
• Time-consuming preparation
• Inaccuracy of dose
• Unsuitabity for many unpleasant tasting, hygroscopic, and deliquescent drug
Disadvantages
are medicated powders usually present in large quantities or volumes and are limited to non-potent substances.
Bulk powders
known as CHARTULA/CHARTULAE
Divided powders
dispensed in individualized doses
Divided powders
examples of these powders are dusting powder, oral powders, triturations, douche, insufflations, and dentifrices.
Divided powders
This method is often used to prevent a gritty feel when solids are incorporated into dermatologic or ophthalmic ointments and suspensions.
Levigation
Triturating it in a mortar and pestle or using an ointment slab and spatula.
Levigation
using an additional materials in which that material is soluble- a volatile solvent that evaporates.
Pulverization by intervention
Examples of volatile solvent
Alcohol
Acetone
What are the types of mortar and pestles
Wedgewood
Glass
Porcelain
Particle sizes are determined by the size of sieve they will pass through generally range from _____ to _____ micron in size.
0.1
10
The size of the particles are often expressed as a ______ which corresponds to the mesh screen size of a sieve.
Number
Other name of divided powders
Chartula
Chartulae