T4 - Liver Flashcards

1
Q

Types of hepatitis (5)

A

Viral
Alcoholic
NAFLD
Drug-induced
Autoimmune

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2
Q

The Hepatitis virus that is spread by ingestion?

A

A and E

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3
Q

The hep virus that is spread parenterally?

A

C

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4
Q

The hep viruses that are spread parenteral, sexual contact?

A

B

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5
Q

All hep viruses are tested for using IgM except for?

A

Hep C

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6
Q

Which hepatitis is more high risk in pregnancy?

A

Hep E

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7
Q

IgM is ______ it leaves 6mo after an acute infx.
IgG ___ it will be present after infection.

A

Immediate.
Stays.

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8
Q

Someone who has a negative anti-HBs

A

Has never had HBV or vaccine - they are susceptible.

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9
Q

Someone who has a positive anti-HBs. AND a positive anti-HBc

A

Is immune to HBV from a natural infection.

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10
Q

Anti-HBs positive shows immunity through ______
Anti-HBc positive shows immunity through _____

A

Vax
Natural infx.

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11
Q

If the HBsAg is positive:

A

The patient has a current acute or chronic HBV infx.

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12
Q

POs IgM anti-HBcand negative anti-HBs means

A

Acute infection.

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13
Q

What should you consider before selecting medication to treat HEPC

A

There are different genotypes of HCV - need to test to see which one to select the best medication to target that specific genotype.

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14
Q

Screening for HCV

A

18 and older - once lifetime
<18 - if risky behavior.
Routine prenatal screening with every pregnancy.
Annual for IV drug users and HIV infected MSM and MSM who take PrEP.

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15
Q

_____ % of HCV infections clear, and ______% are chronic.

A

15-25%
75-85%

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16
Q

______% of chronic HCV patients develop cirrhosis over 20 year.

A

10-20%

17
Q

2 step testing for HCV:

A

Antibody - negative - no infx
Positive -> HCV RNA -> positive: current HCV infx, Negative, past infx

18
Q

T/F: the gold standard for dx of cirrhosis is liver biopsy and it is always performed.

A

False.Gold standard IS liver biopsy, but many risks, so alternatives are usually used.

19
Q

Most common Hepatitis causes?

A

Hep C and alcohol

20
Q

How does a fibroscan work?

A

It measures the stiffness of the liver to stage the degree of liver fibrosis.

21
Q

Earliest s/s of liver cirrhosis:

A

Pruritis, wt loss, fatigue, weakness, malaise, dark urine and pale stools.

22
Q

What MELD-Na score do you need to refer for liver transplant?

A

> 17

23
Q

3 types of HIV testing - which one can give you the earliest recognition?

A

NAT test - w/in 10-13 days of exposure. The rest are over 18-90 days.

24
Q

interdisciplinary care for patients with HIV

A

SW, MH, nutrition, substance abuse, dental, ophtho, colonoscopy, mammogram, pap (if age appropriate) and ID.

25
Q

Your HIV + patient presents with oral thrush. What should you do?

A

Start prophy for pneumocystitis PNA

26
Q

If you patient with HIV has a CD4 ct below 200, then

A

Start daily Bactrim for infx prophy.

27
Q

In an acute HIV infection, the viral load will be ____ and the CD4 count will be ____. As the acute phase wanes, these levels with alternate. Don’t confusion this _____ CD4 count with the ____ CD4 count in AIDS.

A

Hight
Low
Low
Low

28
Q

How often do you f/u with patients with HIV?

A

3-6mo

29
Q

Administer PEP no later than ______

A

72hours post exposure

30
Q

T/F: PEP is safe during pregnancy

A

True.

31
Q

Why should you repeat HIV testing in 24weeks for a patient who is co-infected with HepC?

A

HepC has been shown to delay the HIV sero-conversion.

32
Q

What must you do before starting PrEP?

A

Documented negative 4th gen HIV test.
Rapid HIV POC HIV test negative and no high risk sex 3 weeks prior to starting
No s/s of acute HIV infection
Normal renal fxn
Doc Hep B SAb POs.

33
Q

After starting PrEP, follow up in _____. What should you assess at this f/u visit?

A

3mo
Med adherence, HIV test, behavioral risk support, med SEs, STI s/s, renal fxn, STI test Q6 o.

34
Q

T/F: your patient has been prescribed PrEP. They are protected right after their first dose.

A

False. PrEP takes 7 days for adequate rectal tissue protection, and 20 days for blood and vaginal tissue protection.