T3C C2 le stress chronique Flashcards

1
Q

stress chronique

A

agent stresseur trop intense/ recurrent et des effets deleteres peuvent apparaitre

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2
Q

symptomes stress chronique

A
  • physiques (douleurs, desordres intestinaux)
  • cognitifs (difficulte memorisation/ apprentissage)
  • emotionnels (anxiete, depression, fatigue)
  • comportementaux (tristesse, agressivite)
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3
Q

effet stress chronique niveau hypothalamus

A
  • expression recepteurs cortisol neurones NPV diminue => retrocontrole cortisol moins efficace
  • expression recepteurs GABA neurones NPV diminue => effet inhibiteur du NT par NPV moins efficace
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4
Q

mecanismes affaiblis par stress chronique

A
  • inhibition NPV par NPO
  • boucle retroaction negative exercee par cortisol sur hypophyse + hypothalamus
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5
Q

effet fortes concentrations CRH

A

modifications systeme limbique + cortex prefrontal => diminution densite substance grise + longueur dendrites

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6
Q

medicaments contre stress chronique

A

benzodiazepines

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7
Q

mode d’action benzodiazepines

A

fixation recepteurs GABA => facilitation effets inhibiteurs GABA NT sur systeme nerveux

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8
Q

effets benzodiazepines (dont ceux negatifs)

A
  • anxiolytiques => diminution anxiete
  • sedatifs => favorisant relaxation + sommeil
  • myorelaxant => favorisant relaxation musculaire
  • secondaires => troubles attention, comportemental, memoire, somnolence + peut induire addiction
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9
Q

pratiques non medicamenteuses

A
  • hypnose
  • meditation pleine conscience (MBSR)
  • EMDR
  • ASMR
  • yoga
    => agissent au niveau systeme limbique => diminution symptomes emotionnels, physiologiques + comportementaux
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10
Q

effets stress chronique amygdale

A
  • hausse memoire peur
  • hausse memoire anxiete
  • hausse memoire agressivite
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11
Q

effets stress chronique hippocampe

A
  • trouble memoire spatiale
  • trouble apprentissage
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12
Q

effets stress chronique cortex prefrontal

A
  • alteration attention/ memoire de travail
  • perte adaptation comportementale + capacites de controle et autoregulation
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