T2 biochem Flashcards

1
Q

what is precursor of collagen

A

procollagen

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2
Q

what are the functions of collagen

A

makes up cartilage and connective tissue
used widely in cosmetic surgery
for treatment of wrinkle and aging
form structure of bones and give support to the organ
main component of the tendon

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3
Q

what is requirement of hydroxylation of collagen

A

vitamin C

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4
Q

describe 3 abnormalities of collagen

A

osteogenesis imperfecta
scurvy
Ehlers Danlos syndrome

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5
Q

what is enzyme that degrade the collagen

A

collagenase enzyme

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6
Q

what is role of alpha 1 antitrypsin

A

inhibit elastase enzyme

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7
Q

what happened if someone has antitrypsin deficiency

A

emphysema (destruction of elastin fibers in alveolar epithelial)

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8
Q

what is precursor of elastin

A

tropoelastin

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9
Q

keratin is present in

A

hair and nail

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10
Q

what is water soluble form of collagen after denaturation

A

gelatin

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