L6 biochem Flashcards
1
Q
explain functions of glycine?
A
- heme synthesis
- glutathione synthesis
- purine synthesis
- conjugation of bile acid
- synthesis of collagen
- detoxification
- creatine synthesis
- hippuric acid
2
Q
describe biosynthesis of glycine or source of glycine?
A
- from serine AA
- from threonine AA
- glyoxylate
- carbon dioxide and ammonia
3
Q
what serine needs to form glycine?
A
enzyme- hydroxymethyl transferase
coenzyme- PLP
THFA dependent
4
Q
what threonine needs to form glycine?
A
enzyme-threonine aldolase
coenzyme-PLP
5
Q
what carbon dioxide and ammonia needs to form glycine ?
A
glycine synthase
N5, N10 THFA
6
Q
glyoxylate need what to form glycine
A
oxidative deamination: glycine oxidase
transamination: glycine aminotransferase and PLP
