T1L2 - Intro to Physiology Flashcards
Physiological
normal function in the body of salts/electrolytes
Non-physiological [4]
○ Pathological = abnormal function in the body (disease)
§ Some people will say that “Non physiological = pathological”
○ Events only possible in a laboratory = function outside the body
§ Example: a cell that has intracellular Barium instead of sodium
○ The body, but NOT in relation to function = structure
§ Which is anatomy
○ Normal function in the body of enzymes or antibodies
Physiology helps us to… [3]
• Understanding what is happening in the patient
Understand why the current cure fails to work on so many patients
Understand the pathways for making better cures
Pathophysiology
The mechanism by which a disease process causes the organ to fail
Carbonic anhydrase
• Contributes indirectly to H+ crossing cell membrane (& across epithelia)
§ H+ is charged and cannot cross readily cross cell membranes
§ CO2 is uncharged and readily crosses the membrane
• Helps indirectly to transport CO2 around body
§ CO2 is poorly soluble in blood
H+ and HCO3- are highly soluble