T1L18: Principles of the Nervous System 2 Flashcards

1
Q

Peripheral nerves arise [2]

A

Brain/brainstem = cranial nerves

Spinal cord = spinal nerves

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2
Q

Spinal nerves overview [4]

A

Sympathetic supply to whole body

Motor and sensory supply to whole body except head and neck
Excellent segmental organisation

1 pair at each vertebrae

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3
Q

31 pairs of nerves

A
8 Cervical: Upper limb/head/neck 
12 thoracic 
5 lumbar 
5 sacral 
1 coccylgeal
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4
Q

Dorsal and ventral roots [4]

A

Nerve roots connect spinal nerves to spinal cord
Ventral root = efferent (motor/sympathetic)
Dorsal root = afferent (sensory)
Root sit within vertebral canal

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5
Q

Spinal nerves [4]

A

Dorsal and ventral roots merge to form spinal nerves

Mixed nerves (motor/sensory and sympathetic)

Mixed = efferent and afferent nerves

Exit through intervertebral foramen

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6
Q

Primary rami [3]

A

Spinal nerve divide into

Dorsal/posterior primary ramus

Ventral/anterior primary ramus

Mixed nerves

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7
Q

Dorsal primary ramus [3]

A

Skin over paravertebral gutter

Erector spinae muscles

Facet joints of vertebral column

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8
Q

Ventral primary ramus [2]

A

Supply rest of body

Larger nerves

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9
Q

Map of ventral primary rami [4]

A

• From intercostal nerves and 4 nerve plexuses
• Nerve plexus is where ventral primary rami merge
• Formed nerves contain axions from multiple spinal nerves
Important for innervation to limbs

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10
Q

Dermatomes and myotomes

A

Dermatome: Individual area of skin innervated by single spinal nerve (primary ramus)

Myotome: An individual muscle group innervated by a single spinal nerve (primary ramus)

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11
Q

Embryonic development of dermatomes and myotomes [2]

A

Dermatomes and myotomes develop from somites (mesoderm) during embryonic week 3

Somites are paired blocks from horizontal bands

One pair of spinal nerves (ectoderm) grow into one pair of somites

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12
Q

Dermatome: Clinical importance [2]

A

Loss/altered sensation/pain from dermatome indicates injury to spinal cord, nerve root or spinal nerve
○ Easy to determine location of injury from dermatomes
○ E.g. loss of sensation from skin over umbilicus may indicate damage to……

Also, visceral (organ) pain can be referred to skin (dermatomes) as cutaneous pain
§ E.g. Diaphragm irritation referred to shoulder
(C3-C5 dermatomes)

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13
Q

Myotomes [3]

A

Conserved in thorax

Intercostal muscles supplied by intercostal nerves (T1-T11)

More complicated in limbs

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14
Q

Autonomic component [4]

A

Involuntary part of peripheral nervous systems

	○ Regulate operation of internal organs 
	○ Maintains internal environment 

Sympathetic or parasympathetic

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15
Q

Sympathetic vs parasympathetic

A

Sympathetic function
• Flight or fight
• Maximise use of metabolic resources

Parasympathetic function
• Opposite to sympathetic division
• Switched on during resting
Increases/conserves metabolic resources

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16
Q

Parasympathetic origin

A

Brainstem

Sacral spinal cord

17
Q

Sympathetic origin

A

Thoracic/lumbar spinal cord

18
Q

Anatomy of ANS

A

Preganglionic neuron - postganglionic - effector

Preganglionic - adrenal medulla

19
Q

Sympathetic trunk

A

Spinal cord - spinal nerves - symp trunk - primary rami - MSK or heart/lungs/head

20
Q

Prevertebral ganglia

A

Spinal cord - spinal nerves - splanchnic nerves - prevertebral ganglia and abdomen

21
Q

Sympathetic pathways summary

A

MSK & Heart/lungs/head - noradrenaline

Adrenal medulla - acetylcholine

22
Q

Sympathetic trunk

A

Postganglionic axons exit via spinal nerves to MSK
- contraction of BV, piloerection, sweating

Postganglionic axons exit through branches to heart, lungs or head
- bronchodilation., increase CO, pulp dilation, increase sweating

23
Q

Prevertebral ganglia

A

Some preganglionic axons enter splanchnic nerves and pass to paravertebral ganglia in abdomen

Postganglionic axons

24
Q

Postganglionic axons

A

project to abdominal/pelvic organs

Inhibit peristalsis/gastric secretions, stimulate glucagon release

25
Q

Sympathetic division

A
• Cardiac muscle        
	• Bronchi of lungs        
	• Sweat glands        
	• Hair follicles            
	• Blood vessels        
	• Abdomino-pelvic viscera
Eye
26
Q

Parasympathetic division

A

• Cardiac muscle - HR/contraction decreases
• Bronchi of lungs - narrow bronchi
• Sweat glands - NA
• Hair follicles - NA
• Blood vessels - NA
• Abdomino-pelvic viscera- stimulate peristalsis and gastric secretions
• Eye - constrict pupil
Salivary glands - secrete saliva

27
Q

Cranial parasympathetic

A

Cell bodies of preganglionic neurons in brainstem
Ganglia located close to effector organs

Pupil - constriction
Lacrimal gland - tears
Parotid/submandibular gland - saliva production

28
Q

Cranial parasympathetic: Vagus nerve

A

Lungs - bronchoconstriction
Heart - Decrease CO
Abdominal organs - peristalsis

Preganglionic axons synapse with postganglionic axons close to/on viscera

29
Q

Sacral parasympathetic

A

Preganglionic axons exit via pelvic splanchnic nerves

Synapse with postganglionic axons of pelvic organs

Bladder - urination
Rectum - defecation