T cells and acquired immunity

Question 1

where do T cells originate
What is their stem cell name
Where do they mature (develop immunocompetence)

Answer 1

bone marrow
lymphoblast
thymus

Question 2

how do T cells facilitate cell mediated immunity

Answer 2

direct attack of antigens

Question 3

what do cytotoxic T cells do to infected cells, tumor cells, and non self-cells

Answer 3

Lyse them

Question 4

what protein causes lysing of antigens
how does it function

Answer 4

perforin

forms a hole in the plasma membrane of
the target cell

Question 5

what do cytotoxic T cells produce
what do these products promote

Answer 5

interferons and interleukins
phagocytosis and inflammation

Question 6

what is the function of Helper T cells

Answer 6

aid in proliferation and activation of cytotoxic T cells

Question 7

what is the function of regulatory T cells

Answer 7

suppress overactivity and autoimmune response

Question 8

what is the function of memory T cells

Answer 8

improve response to secondary exposure

Question 9

what is active immunity

Answer 9

immunity provided by own self

Question 10

explain natural active immunity

Answer 10

get sick due to direct antigen exposure to initiate primary exposure response and memory for stronger secondary response

Question 11

explain artificial active immunity

Answer 11

antigen introduced in vaccine to initiate response (and memory)

Question 12

what is passive immunity

Answer 12

immunity transferred (antibodies) from another source (NOT made by one’s own body)

Question 13

give an example of natural passive immunity

Answer 13

antibodies from mother to child across placenta or milk

Question 14

give an example of artificial passive immunity

Answer 14

antibodies from another source are injected (monoclonal antibodies)