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BRS Year 2 > systemic skin basics > Flashcards

systemic skin basics Flashcards

1
Q

distrib of dermatomyositis

A

extensor surfaces (both muscle weakness and rashes)

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2
Q

skin systemic disorders

A 
SLE
dermatomyositits
vasculitis
granulomatosis with polyangiitis 
sarcoidosis
systemic amyloidosis
graft vs host
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3
Q

types of lupus erythmatous

A

neonatal
systemic
cutaneous/discoid

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4
Q

what does SLE affect

A 
liver
kidney
skin
joints
brain
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5
Q

what does discoid lupus look like

A

coin shaped lesions
scaly, thick, red
dont hurt or itch

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6
Q

signs of SLE

A 
photodistrubuted rash - butterfly
subacute cutaneous lupus
livedo reticularis
chillblains
palpable purpura
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7
Q

neonatal lupus risks

A

ECG needs to be done as they have risk of heart block

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8
Q

presentation of dermatomyositis

A 
photodistrubuted
pink violet
extensor surfaces and periocular
upper trunk redness (shawl and V sign)
gouttrons papules on fingers
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9
Q

presentation of vasculitis

A

purpura
digital necrosis
retiform purpura ulcers & subcutaneous nodules following blood vessel

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10
Q

presentation of granulomatosis with polyangiitis

A

cough chest pain stuffy nose nosebleeds
palpable purpura
retiform purpura and subcutaneous nodules

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11
Q

sarcoidosis presentation

A 
lupus pernio (bluish red) over nose cheeks ears
very variable - great mimicker
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12
Q

sarcoidosis

A

diagnosis of exclusion

causes granulomas to form in organs particularly lungs and skin

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13
Q

systemic amyloidosis

A

amyloid deposits in tissue

can cause organ failure

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14
Q

presentation of systemic amyloidosis

A

wt loss, fatigue
dyspnoea + syncope
periorbital purpura/racoon sign

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15
Q

graft vs host disease

A

donor T cells attack antigens in recipient who is immunosuppressed
acute or chronic
stem cell transplants

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16
Q

graft vs host presentation

A

alloimmune
skin, liver, gi tract
face/ acral involvement and diarrhoea

17
Q

GvH vs drug reaction

A

GvH face and acral (extremities) involved

diarrhoea

18
Q

DRESS

A

drug reaction with eosinophilia and systemic symptoms

2-6wk after exposure

19
Q

presentation of DRESS

A 
fever
rash - widespread, face, upper trunk+extrems
lymphadenopathy
peripheral eosinophilia
2-6wk after drugs
facial oedema
20
Q

treatment of DRESS

A

withdraw drug

corticosteroids

21
Q

steven johnson syndrome

A

full thickness mucocutaneous necrosis

22
Q

steven johnson syndrome presentation

A

history of flu sympt
acute onset
macules blisters and erythema
sheets of skin detachment

23
Q

steven johnson syndrome vs toxic epidermal necrolysis

A

more than 30% skin detachment of steven johnson = TEN

24
Q

erythroderma

A

generalised eythema over 90% body surface

can be idiopathic, drug induced, T cell lymphoma (sezary snd) psoriasis, eczema

25
Q

management of erythrodema

A

underlying cause
fluids etc
emollients
steroids / ABs

26
Q

how can gi conditions present on skin

A

IBD - pyoderma gangrenosum and panniculitis

coeliac - dermatitis herpetiformis

27
Q

skin manifestation of nutritional deficiencies

A

scurvy - bleedin of gums, petechiae, corkscrew hairs, follicular hyperkeratosis
zinc - dermatitis diarrhoea depression
niacin/B3 - dermatitis diarrhoea dementia death

28
Q

CKD skin symptoms

A

pallor
excoriations
calciphylaxis - clots ulcers necrosis etc
half half nails

29
Q

liver disease skin signs

A 
jaundice
terrys nails and muehrckes nails
clubbing
spider naevi
palmar erythema
excoriations
30
Q

immunodeficiency skin signs

A

opportunistic infections - viral warts

HIV - kaposis sarcoma

31
Q

DM skin signs

A 
acanthosis nigricans
xerosis
skin infections
feet ulcers
necrobiosis lipoidica
granuloma annulare
32
Q

hyperlipidaemia skin signs

A

xanthomas

xanthelasma

BRS Year 2 (67 decks)

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