Dementia Flashcards

1
Q

alzheimers

A

neurodegenerative disorder characterised by progressive cognitive, social and functional impairment

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2
Q

causes of dementia

A

Alzheimer’s
Vascular dementia
Frontotemporal dementia
Lewy body dementia

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3
Q

reversible causes of dementia

A
Depression
Alcohol related brain damage
Endocrine
Vitamin B deficiencies
Benign Tumors
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4
Q

what is dementia

A

severe loss of memory and other cognitive abilities which leads to impaired daily function (regardless of the underlying cause)

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5
Q

dementia investigations

A

Neuropsychology
Bloods
MRI
PET

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6
Q

bloods for dementia

A
FBC
Inflammatory markers
Thyroid function
Renal function
Glucose
B12 and folate
Clotting
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7
Q

MRI results for alzheimers

A
Narrow gyri
Widened sulci
Ventricles dilate
Medial temporal volume loss
Hippocampus volume loss
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8
Q

management for dementia

A
Acetylcholinesterase inhbitors
Watch and wait
Treat behavioural symptoms
Anti-depressants
Social Services
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9
Q

alzheimers presentation

A

subtle, insidious onset

amnesia

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10
Q

presentation of vascular dementia

A

step wise deterioration

related to underlying CV disorder

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11
Q

lewy body dementia presentation

A

fluctuations in cognition

Cognitive impairment before/within 1 year of parkinsonian symptoms, visual hallucinations

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12
Q

presentation of frontotemporal dementia

A

behavioural issues
semantic dementiA
progressive non fluent aphasia

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13
Q

what is the mMSE

A

mini mental state examination

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14
Q

what is the ACE screening tool

A

addenbrooks cognitive assessment

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15
Q

episodic memory

A

Memory for a particular life events

Dependent on the medial temporal lobes including the hippocampus

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16
Q

how does lewy body dementia look on MRI

A

preserved hippocampal volume

17
Q

what section of ACE may someone wih alzheimers struggle

A

name address

acute memory

18
Q

what must be taken into account during an ACE

A

context of individual - socioeconomic status
educational background
political awareness
social interactions

19
Q

what may show visuospatial issues within the ACE

A

drawing
indentifying partial letter
looking at diagrams, counting spots without pointing

20
Q

delirium vs dementia

A

delirium related to physical condition and acute

dementia long standing, usually unchanging based on environment

21
Q

what is the head turning sign of alzheimers

A

looking around to see others’ answers to question as they dont know the answer

22
Q

CSF results for alzheimers

A

lower amyloid

higher Tau proteins

23
Q

what specific marker on PET scan is there for lewy body dementia

A

decreased dopamine transporters caudate and putamen

24
Q

what MRI sign can show frontotemporal dementia

A

loss/atrophy and assymetry of peri-sylvian fissure

25
Q

what MRI sign can show frontotemporal dementia

A

loss/atrophy and assymetry of peri-sylvian fissure