Systemic Lupus Erythematosus Flashcards
All of the following are TRUE about epidemiology of SLE EXCEPT:
A. 30% of patients are women of child-bearing years
B. Prevalence is higher in all white races
C. 2-3.5 times more prevalent in women than men
D. All of the options
D. All of the options
Which of the following autoantibodies is specific to SLE and has no definite clinical correlations?
A. ANA
B. Anti-dsDNA
C. Anti-Sm
D. Anti-C1q
E. Anti-RNP
C. Anti-Sm
All of the following are TRUE about ANA EXCEPT:
A. Best screening test
B. Immunofluorescence is best standard test
C. Has good specificity but poor sensitivity
D. None of the options
C. Has good specificity but poor sensitivity
All of the following increases the risk for SLE EXCEPT:
A. Tobacco smoking
B. Alcohol
C. Exposure to crystalline silica
D. Exposure to UV rays
E. Long term exposure to air pollution
B. Alcohol
SLE biopsies reveal all of the following EXCEPT:
A. deposition of Ig at the DEJ
B. injury to basal keratinocytes
C. Inflammation dominated by B lymphocytes in the DEJ
D. None of the options
C. Inflammation dominated by B lymphocytes in the DEJ
All of the following classes of lupus nephritis are treated with aggressive immunosuppression EXCEPT:
A. Class III
B. Class IV
C. Class V w/ III or IV
D. Class VI
E. None of the options
D. Class VI
Involves glomerulonephritis involving <50% of all glomeruli
A. Class I (Minimal Mesangial)
B. Class II (Mesangial Proliferative)
C. Class III (Focal)
D. Class IV (Diffuse)
E. Class V (Membranous)
C. Class III (Focal)
All of the following are chronic cutaneous skin manifestations of SLE EXCEPT:
A. Discoid rash
B. Lichen planus-like
C. Bullous
D. Chillblains
E. Panniculitis
C. Bullous
Thrombocytopenia in SLE is described as which of the following?
A. <200,000/uL
B. <150,000/uL
C. <100,000/uL
D. <50,000/uL
E. <10,000/uL
C. <100,000/uL
If pain persists in a single joint, such as knee, shoulder, or hip, a diagnosis of which of the following should be considered?
A. SLE
B. Arthritis
C. Rhupus
D. Ischemic necrosis of bone
D. Ischemic necrosis of bone
Most common chronic dermatitis in lupus
A. Discoid
B. Panniculitis
C. Verrucous
D. Chillblains
A. Discoid
Butterfly rash
A. Acute
B. Subacute
C. Chronic
D. Any of the options
A. Acute
Annular lesions
A. Acute
B. Subacute
C. Chronic
D. Any of the options
B. Subacute
Most serious manifestation of SLE
A. Pericarditis
B. Nephritis
C. Pleuritis
D. Seizures
B. Nephritis
Most common manifestation of diffuse CNS lupus
A. Seizure
B. Psychosis
C. Cognitive dysfunction
D. Delirium
C. Cognitive dysfunction