Systemic Corticosteroids Flashcards

1
Q

Mechanism of action

A

Decrease inflammation

Increase response to B2 agonists

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2
Q

Methylprednisolone dosage form

A

tablet

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3
Q

Methylprednisolone age range

A

all ages

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4
Q

Prednisolone dosage forms

A

Tablets

Oral liquid

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5
Q

Prednisolone age range

A

All ages

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6
Q

Prednisone dosage forms

A

Tablets

Oral liquid

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7
Q

Prednisone age range

A

All ages

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8
Q

Dexamethasone dosage forms

A

Oral Liquid
Tablets
Injection

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9
Q

Dexamethasone age range

A

All ages

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10
Q

Methylprednisolone acetate dosage form

A

Respiratory injection

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11
Q

Methylprednisolone acetate age range

A

all ages

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12
Q

AE and Clinical Pearls

A

AE: short term use-hyperglycemia, increased appetite, fluid retention, demargination of WBCs, psychiatric disturbances
CI: Systemic fungal infections, administration of live vaccines if immunocompromised
DI: Warfarin INR increases, decreased efficacy of inactived vaccines
May be used with ICS if patient is already taking ICS before hospitalization
May also be used for chronic therapy in both asthma (and COPD) only in severe stages
“Bursts” effective for establishing control when initiating therapy or during period of gradual deterioration
Injection may be used in place of “burst” if adherence is an issue or patient is vomiting

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