Inhaled Short Acting B2 Agonists Flashcards
Mechanism of action
Increased cAMP, antagonizes bronchoconstriction –> smooth muscle relaxation (reverse obstruction and improve air flow)
Albuterol HFA brand names
ProAir
Ventolin
Proventil
ProAir Respiclick
ProAir, Ventolin, and Proventil dosage form
MDI
ProAir Respiclick dosage form
Aerosol Powder Inhaler
Albuterol HFA age range
All ages
Albuterol HFA AE and Clinical Pearls
AE: Tachycardia, tremor, hypokalemia, irritability
Chronic use (>2 times per day) indicates poor asthma control
May mix nebulizer solution with cromolyn solution, budesonide inhalant suspension, or ipratropium solution
In mild to moderate exacerbations, MDI plus valved holding chamber is as effective as nebulized therapy with appropriate administration technique and coaching by trained personnel
Albuterol dosage form
Nebulizer solution
Albuterol age range
all ages
Levalbuterol HFA brand name
Xopenex
Levalbuterol HFA dosage form
MDI
Levalbuterol HFA age range
All ages
Levalbuterol HFA AE and Clinical Pearls
AE: Tachycardia, tremor, hypokalemia, irritability
Reserved for patients who do not respond to albuterol for quick relief
Nebulizer solution compatible with budesonide inhalant suspension
Levalbuterol administered in 1/2 the mg dose of albuterol provides comparable efficacy and safety
Has not been evaluated by continuous nebulization
Levalbuterol dosage form
Nebulizer solution
Levalbuterol age range
All ages