Syrups (Exam 2) Flashcards
Syrups
concentrated sugar with or without flavoring and drugs
All syrups are
sweet and viscous
Can diabetics have regular syrups?
NO
Nonmedicated syrups
Pleasant-tasting to add into prescription compounding
Basis for flavored or medicated syrups
Simple syrup
Vehicles for drugs stable in acidic medium
cherry and orange syrup
Masking for bitter-tasting drugs
Cocoa syrup
Masking salty/sour tasting drugs
Raspberry syrup
Sugar free nonmedicated syrup
Ora-Sweet (SF)
Advantages of mediated syrups
pleasant taste & formulation
little-no alcohol
those who cant swallow pills
Proper selection of syrup
solubility
stability in aqueous + pH mediums
compatibility
Glycogenetic compounds
sucrose
sorbitol
gylcerin
propylene glycol
Glycogenetic compounds are responsible for
viscosity
sweetness
flavor
Components of medicated sucrose-based syrups
drug
purified water
cosolvent
sugar
preservative
flavorant
colorant
Does Sucrose NF (Simple Syrup) need a preservative?
Not if it will be used soon
Sucrose NF (Simple Syrup) uses
basis for flavored or medicated syrups
sugar coating to tablets
Oral sorbitol is a laxative at dose _____.
> 20 g/day
Non sucrose based syrups contain
artificial sweeteners
viscosity inducing agents
viscosity inducing agents
methycellulose
carboxymethylcellulose
hydroxyethylcellulose
viscosity inducing agents are not absorbed into the ______
blood
Components of non sucrose based syrups
same as sucrose based but artificial sweetener instead of sugar
Artificial sweeteners
Saccharin NF
Saccharin Sodium USP
Aspartame
Syrup preservatives
Benzoic acid/sodium benzoate
combos of parabens
alcohol 15-20%
high sucrose conc.
storage at low temps
Colorant should be ____ with the flavorant
correlated
pink w strawberry
Syrups have to be stored in ____
tight containers
Preparation of syrups
Use heat
shake/mix
add sucrose
excessive heat may inverse _____ into _____ and ______
sucrose
dextrose and fructose
speed of sucrose inversion increases in
acidic medium
results of inversion
less stable
altered sweetness and color
agitation of solutions
maximum stability
time consuming
avoid use of heat
admixture of solution
dissolve drug in small amount of water then incorporate into syrup
Miscible medicated liquids should be added _____ to simple or flavored syrup
directly
commercially available medicated syrups
analgestic
antiviral
antihistamines
antipsychotic
