Granules Flashcards

1
Q

granules

A

prepared agglomerates of smaller particles of powder

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2
Q

size and shape of granules

A

4-12 sieve
irregular or spherical shaped

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3
Q

how to prepare granules?

A

wet method
dry method

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4
Q

basic wet method

A

moisten the powder
pass the paste through a screen of mesh
dry the granules by air/heat on drying trays

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5
Q

fluid bed method

A

place particles in conical equipment
spray liquid excipient on vigorously dispersed and suspended particles
dry

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6
Q

dry granulation method

A

light compaction of powder material
compacted powder broken to granules

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7
Q

dry granulation method is commonly used for materials that are

A

moisture sensitive

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8
Q

administration of granules

A

measured and mixed with water
sprinkled on food
eaten plain

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9
Q

effervescent granules and tablets should be

A

dissolved in water before use

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10
Q

effervescent granules provide

A

pleasant vehicle for bitter/salty drugs

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11
Q

effervescent granules composition

A

medicinal agent
sodium bicarbonate
citric acid and tartaric acid

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12
Q

granules or coarse particles decrease the rate of

A

solution and prevent uncontrollable effervescence

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