SYPHILIS STAGING

Question 1

Chancre at site of entry.

Usually three weeks after exposure (10-90 days)

Genitals and anus are usual site

Regional adenopathy is called a bubo

Serologic tests are usually positive

Answer 1

Primary Stage

Question 2

Secondary syphilis: Usually begins 3-10 weeks after chancre, but can overlap

Many cutaneous eruptions can occur, called syphilids or lues

“Great imitator:” Can look like many other benign rashes

Classically mimics pityriasis rosea

Papules and patches, often oval, may be copper colored, generalized, with involvement of palms and soles

All secondary lesions are highly contagious-use gloves to examine

CONDYLOMA LATA
MUCOUS PATCHES

serologic tests positive

Answer 2

Secondary Syphilis

Question 3

Positive serologic test for syphilis without any clinical symptoms or evidence or organism in CSF

Late latent syphilis: Two years beyond initial infection

Answer 3

Latent Syphilis

Question 4

Up to 60 years after initial infection

Gumma: Small nodule, enlarges and necroses

Develops into punched-out ulcer with gummy base

Ulcerative nodules

Aortic aneurism, CNS signs, dementia

Answer 4

Tertiary Syphilis

Question 5

serlogic tests?

Answer 5

RPR, STS, VDRL

Question 6

Low titer indicates ?

Answer 6

latent

Question 7

treated syphilis?

Answer 7

serofast

Question 8

late syphilis?

Answer 8

false positive

Question 9

serologic test is specific or nonspecific?

FTA-ABS?

Answer 9

non specific

specific, permanent

Question 10

treated with?

Answer 10

IM penicillin

Latent and tertiary disease require CSF evaluation, and IV penicillin