HIGH YIELD II Flashcards
Premalignant lesions
40% of population have solar keratoses
Multiple discrete, flat or elevated, verrucous, keratotic lesions on sun
exposed areas
Topicals, photodynamic therapy, biopsy surgery
Lower Extremity Actinic Keratoses
what is this?
Acanthosis,
parakeratosis, and
dyskeratoses
Cellular atypia
Common mitotic figures -Resembles Bowens disease or carcinoma in situ -Marked hyperkeratosis and areas of parakeratosis with loss of the granular layer -Dense inflammatory infiltrate is usually present
AK histology
Red pseudonetwork
Rosette sign
what is this?
Reticular, or net-like, pattern of erythema
Heating pads or blankets, however, laptop computers
Erythema Ab Igne
what is this?
Thermal injury
-Fireplace, potbellied
stove, heating pad
Erythema ab igne
-Acute phase- blanchable reticulated erythema
Surveillance SCC BCC
- TAC, Ammonium lactate
- Retinoid or 5-FU
Toasted Skin Syndrome
*Pigmented seborrheic keratoses arising in field of toasted skin
what is this?
Nodular erythematous eruption of subcutaneous fat -Typically extensor surfaces of legs and or feet -Occasionally occurs on thighs, calves and forearms -Usually resolves spontaneously within several weeks -Bruise like discoloration heals without scarring
Histopathology: septal panniculitis without vasculitis
Erythema Nodosum,
Streptococcal pharyngitis
other triggers
- Urinary Tract Infection
- Tuberculosis
- Sarcoidosis - 28% have EN
- Chlamydia and viral infections
- Deep systemic fungal infections
what is this?
Sun poisoning or sun allergy
Erythematous papules erupting on the evening of the first or second day after increased sunlight exposure
Prevent and treat with short course of oral steroids
*bathing in sea can increase penetrance of UV radiation
polymorphous light eruption
what is this?
Capillaritis
Schamberg’s disease or progressive pigmentary purpura
-commonest pigmented purpura and middle aged adults and children
Pigmented Purpuric Dermatoses
eczema is not a specific diagnosis but a description of a skin_____?
reaction pattern
primary irritant is a type of?
allergic contact dermatitis is what reaction?
contact dermatitis
hypersensitivity reaction
histopathology of contact dermatitis?
in allergic contact dermatitis , what predominates?
spongiosis
lymphocytes
acute eczema presents with?
*chronic eczema?
epidermal edema or spongiosis
separation of keratinocytes leading to formation of vesicles
***acanthosis and parakeratosis
symmetrical linear eruption which spares the toe web spaces
no response to anti fungal therapy
key is removing of offending agents
tx: tapering doses of topical corticosteroid
this is a diagnosis of?
contact dermatitis
what is this?
chronic pruritic inflammatory skin disease
-abnormal filaggrin
children and adults
- 11% of children
- elevated serum of IgE
- personal or family hx of atopy, group of disorders that includes eczema and asthma
- CVD a risk factor
atopic dermatitis
major protein component of keratohyalin granules
filaggrin maintains epidermal flexibility
-barrier fxn
palm reading
-thenar hyper linearity
pro filaggrin defect
localized circumscribed neurodermatitis
Rx: triamcinolone acetonide
AKA: winter itch
asteotic eczema, treated with hydration first with bath salts then low potency corticosteroids
