HIGH YIELD

Question 1

only on palms, soles and digits?

Answer 1

unique feature of thick skin

Question 2

thick skin contains this protein?

Answer 2

eleidin, clear protein rich in lipids, derived from keratohyalin

Question 3

strong characteristic of thick skin?

Answer 3

provides a barrier to water

Question 4

these sensors are found densely packed on palms and soles

Answer 4

Merkel cell pressure sensors

Question 5

Superficial benign
fibrous histiocytoma

Typically dimples with lateral compression

Benign lesions with excellent prognosis

what is this?

Answer 5

Dermatofibroma

Question 6

Venous Hypertension

Typically shallow with
irregular borders with yellow, fibrinous exudate overlying
the wound bed

what is this?

Answer 6

Venous Insufficiency Leg Ulcers

Question 7

Telangiectasias of
the feet and ankles

Hemosiderosis -
brown discoloration

what is this?

Answer 7

Chronic Venous Disease

Question 8

stages of venous skin disease?

Answer 8

chronic venous insufficiency

hemosiderosis

induration

telangiectasia

dry ulcer with crust

atrophy blanche

dermoscopy:ivory white areas with linear and glomerular vessels

Question 9

epidermal changes
-hyperkeratosis, parakeratosis

dermal changes
-dermal fibrosis, hemosiderin laden macrophages

positive iron stain

what is this?

Answer 9

venous stasis dermatitis

Question 10

long-standing venous hypertension

indurated inflammatory tissue that binds the skin down to the subcutaneous tissue

elongated, glomerular like

what is this?

Answer 10

lipodermatosclerosis

Question 11

small skin vessels
-palpable purpura

diagnostic biopsy
-leukocytoclastic vasculitis with infiltration of postcapullary venules

what is this?

Answer 11

vasculitis

Question 12

Mottled reticulated vascular pattern
-Lace-like purplish pattern
-Swelling of the venules due to
obstruction of capillaries by
small blood clots

Common skin finding

Clotting disorders

• Cryofibrinogenemia
• Calciphylaxis

what is this?

Answer 12

lived reticularis

Question 13

AKA Calcific uremic arteriolopathy
-EKSD on dialysis

calcification of dermal and subcutaneous arterioles and capillaries

lethal disease
-six month survival 50 percent

what is this?

Answer 13

calciphylaxis

Question 14

Chronic, painful, ulcerative skin condition

Crusted, painful, stellate, shallow ulcerations

Ulcers heal with white, atrophic, stellate scars
with telangiectasia
-atrophy blanche-healing pattern

cutaneous biopsy

tx: pain management

what is this?

Answer 14

Livedoid Vasculopathy

Question 15

AKA: Rheumatoid vasculitis

Periungual, necrotic lesions

Can form in hand or foot

Cutaneous intimal vasculitis secondary to elevated rheumatoid factors

what is this?

Answer 15

Bywater’s Lesion

Question 16

Most common autoimmune blistering
disorder

many eosinophils
in the blister cavity

IgG and C3 in a linear homogenous
immunofluorescence pattern at the dermoepidermal
junction

what is this?

Answer 16

Bullous Pemphigoid

Question 17

aka hypersensitivity
vasculitis and hypersensitivity angiitis

small-vessel inflammation

Typically a drug reaction

what is this?

Answer 17

Leukocytoclastic

Vasculitis

Question 18

Immunoglobulin A Vasculitis

in children

Classic symptoms include a rash,
abdominal pain, joint pain, edema, scrotal swelling, and bloody stools
-palpable purpura on legs
-arthralgias
-small vessel deposition of IgA elevated 70%

what is this?

Answer 18

Henoch-Scholein Purpura

Question 19

Common, often self-limited reaction:
-Trauma, insect bites

Both children and adults

Localized form
-Nonscaly, erythematous, annular plaque on the distal extremity

Generalized form
-Numerous confluent erythematous papules and plaques on the hands, arms, buttocks and extremities

Answer 19

Granuloma Annulare

Question 20

what is this?

atrophic brown and yellow patch

• Pretibial and medial malleolus
• Fine telangiectasia

0.3% of diabetics

Dermoscopy

• Comma-shaped vessels
• Irregular branching vessels
• Whitish areas of degenerated collagen

Biopsy 3 to 5 mm punch

Answer 20

Necrobiosis Lipoidica

Question 21

what is this?

Acute eruption

• Dark-red, slowly growing painful papules and plaques
• Face and the extremities
• High fever
• Neutrophilic leukocytosis

Children and adults

• URI, GI infections, Chron’s, pregnancy, malignancy, drugs
• ESR >20 mm/hour
• CRP >8000
• > 70% neutrophils

Biopsy
-Dense neutrophilic infiltrate without evidence of leukocytoclastic vasculitis

-Systemic glucocorticoids

Answer 21

Sweet Syndrome

Acute Febrile Neutrophilic Dermatosis

Question 22

what is this?

Childhood vasculitis

Cracked, red lips and strawberry tongue

Skin peeling begins under the nails at 2
weeks
-Large peeling sheets progresses over several
days lasting 12 days
-Extremities manifestation occurs last
-Indurated edema of hands and feet
-Diffuse erythema of palms and soles

Answer 22

Kawasaki Disease

Question 23

what is this?

Hematologic disorder SCD
-Triggers stroke, myocardial infarction

Disproportionate pain

Answer 23

Sickle Cell Disease

Question 24

painful purulent progressive leg
ulcer

what is this?

Answer 24

Enlarging Ankle

Ulcer