Syndrome of Inappropriate ADH Secretion (SIADH)

Question 1

SIADH

Answer 1

• Over secretion of ADH caused by certain drugs leads to increased water reabsorption
• Leads to hyponatremia and low serum osmolarity
• ADH secretion reduction - lithium, demeclocycline
• Excess lithium can cause diabetes insipidus due to failure to produce ADH