Synaptic Transmission

Question 1

Axodendritic synapse

Answer 1

Axon to dendron

Question 2

Axosomatic synapse

Answer 2

Axon to soma

Question 3

Axoaxonic synpase

Answer 3

Axon to axon

Question 4

Contents of presynaptic terminal

Answer 4

Synaptic button

Cytoskeleton

Mitochondria

Synaptic vesicles

Aactive zone

Synaptic cleft

Question 5

Neuromuscular junction

Answer 5

Synapse between neurone and muscle fibre

Question 6

Synaptic transmission

Answer 6

AP reaches synaptic terminal

NT molecules released from PreS neurone

NT diffuse across synpatic celft to PostS membrane

Question 7

Postsynaptic receptor response to NT

Answer 7

1. Direct excitatory or inhibitory neurotransmission
   - membrane slightly depolarised of hyperpolarised
2. Neuromodulation
   - alters PreS cells ability to release more NT or PostS cells ability to respond

Question 8

Criteria that define a neurotransmitter

Answer 8

1. Synthesised in the neurone
2. Present in PreS teminal and released to exert effect on PostS neurone or effector organ
3. When administered exogenously it mimics as of endogenous NT
4. Specific mechanism exists for removing it from cleft