Synaptic transmission Flashcards

1
Q

Synaptic transmission

A

The process by which neighbouring neurons communicate with eachother by sending chemical messages across the synapse that separates them

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2
Q

Synapse

A

Gap between neurons

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3
Q

What charge do neurons have in its resting state inside of the cell?

A

negatively charged

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4
Q

What charge does a neuron get when it’s activated by a stimulus?

A

positive charge for a split second

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5
Q

action potential

A

a neural impulse; a brief electrical charge that travels down an axon, changing from negative to positive.

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6
Q

electric transmission

A

A neuron is rested inside of a negatively charged cell
The neuron is activated, the cell becomes positively charged causing an action potential
This creates an electrical impulse that travels down the axon towards the end of the neuron.

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7
Q

pre-synaptic neuron

A

a neuron that delivers a signal to a synapse
transferring the action potential

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8
Q

post-synaptic neuron

A

the neuron receiving the action potential

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9
Q

what does the synapse include

A

end of the pre-synaptic neuron, membrane of the post synaptic neuron and the gap inbetween

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10
Q

Synaptic cleft

A

the physical gap between the pre-synaptic neuron and the post-synaptic neuron

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11
Q

synaptic vesicles

A

contain chemical messengers known as neurotransmitters which assist in the transfer of action potential

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12
Q

Exocytosis

A

when action potential reaches the vesicles and it causes them to release their contents

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13
Q

re-uptake

A

a neurotransmitter’s reabsorption by the pre synaptic neuron and is stored for later release

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14
Q

Neurotransmitters

A

chemical messengers that carry signals from the pre-synaptic neuron across the synaptic cleft to the receptor site on the post synaptic neuron

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15
Q

Which two ways can neurotransmitters be classed?

A

Excitatory or inhibitory

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16
Q

inhibitory neurotransmitters

A

responsible for calming the mind and body including sleep and filtering out any unnecessary excitatory signals

17
Q

excitatory neurotransmitters

A

likely to increase your chances to activate or carry out a behaviour

18
Q

What are examples of excitatory neurons?

A

adrenaline and dopamine

19
Q

What are examples of inhibitory neurons?

A

GABA and serotonin

20
Q

What happens when an excitatory neurotransmitter binds to a post synaptic receptor?

A

Excitatory post synaptic potential (EPSP)

21
Q

excitatory postsynaptic potential (EPSP)

A

The post synaptic cell is more likely to fire because an excitatory neurotransmitter has blinded to a post synaptic receptor causing an electrical charge in the membrane of the post-synaptic neuron

22
Q

What happens when an inhibitory neurotransmitter binds to a post synaptic receptor?

A

Inhibitory post synaptic potential (IPSP)

23
Q

inhibitory postsynaptic potential (IPSP)

A

The neuron is less likely to fire as an inhibitory neurotransmitter gas blinded to a post synaptic receptor

24
Q

How is the likelihood of a cell firing determined if it receives both EPSP and IPSP at the same time?

A

adding up the excitatory and inhibitory synaptic input

25
Which two ways can the strength of an EPSP be increased?
spatial summation and temporal summation
26
spatial summation
a large number of EPSPs are generated at many different synapses on the same post-synaptic neuron at the same time
27
temporal summation
a large number of EPSPs are generated at the same synapse by a series of high-frequency action potentials by a pre-synaptic neuron
28
what determines the rate at which a particular cell fires?
What goes on in the synapse, if excitatory synapses are more active the cell fires at a high rate if inhibitory synapses are more active it will be at a lower rate if at all