Synaptic plasticity Flashcards

1
Q

Pavlovian conditioning

A

Association between a neutral stimilus and a positive or negative stimulus.

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2
Q

Operant conditioning

A

Associating a voluntary behaviour with a concequence.

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3
Q

Tone-cued fear

A

Hippocampus independent, Amygdala dependent

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4
Q

Contextual fear

A

Hippocampus dependent, amygdala dependent.

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5
Q

The objects location memory task requires:

A

Hippocampus

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6
Q

The rotarod task requires:

A

Motor cortex and cerebellum

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7
Q

Anisomycin

A

Protein synsthesis inhibitor. New proteins are the essential building blocks to strengthen neuronal connections

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8
Q

Protein synthesis is required for:

A

Making new axonal-dendritic connections

Strengthening existing connections

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9
Q

Synaptic plasticity

A

Process of making new connections and/or changing the strength of existing connections.

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10
Q

Long-term potentation (LTP)

A

Form of synaptic plasticity and the molecular basis of memory storage.

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11
Q

E-LTP

A

A weak form of learning that is not persistent. (Short-term memory that is not consolidated into long-term memory)

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12
Q

EPSP

A

Measure of relative strength of the neuronal connections before and after stimulation

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13
Q

L-LTP

A

A strong form of learning that is persistent (Short-term memory that is succesfully consolidated into long-term memory)

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14
Q

NMDA receptors

A

Essential for LTP induction and the initiaition of memory formation.

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15
Q

Cofilin

A

Protein that breaks down spines when it is activated. (highly activated in sleep-deprived hippocampus)

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