Cholinergic system/Alzheimer's Disease Flashcards

1
Q

Modulatory systems

A
  1. serotonine
  2. dopamine
  3. noradrenaline
  4. acetylcholine
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2
Q

The essence of learning and memory:

A

strengthening of synaptic contacts

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3
Q

The cholinergic system is crucial for:

A

Attention and the starting point of a learning process

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4
Q

Acetylcholine is made from:

A

Choline and acetyl CoA

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5
Q

Function of the enzyme acetylcholinesterase

A

Breaks down Ach in the synaptic cleft

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6
Q

The two types of cholinergic receptors:

A
  1. Nicotinic receptor

2. Muscarinic receptor

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7
Q

Social contacts and stressfull event play a role in ….

A

The formation of alzheimers disease

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8
Q

Tau protein

A

Anchors the mircotubules, when the proteins are gone the entire structure of the cell collapses.

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9
Q

Extracellular amyloid plaques

A

Consisting of amorphous extra cellular deposists of aß protein. Outside the neuron

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10
Q

Neurofibrillary tangles

A

Comprising of filaments of phosphorylated Tau protein, Inside the neuron.

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