Sympathomimetics

Question 1

epinephrine

Answer 1

low dose: B>a

high dose: a>B

Question 2

NE

Answer 2

a1 > a2 >B1

Question 3

isoproterenol

Answer 3

b1=b2

Question 4

dopamine

Answer 4

D1=D2>B>a

high dose, a>B

Question 5

dobutamine

Answer 5

B1 > B2 > a

Question 6

phenylephrine

Answer 6

a1 > a2. nasal decongestant

Question 7

albuterol

Answer 7

B2 > B1

Question 8

a2 effect

Answer 8

decrease sympathetics, decrease insulin, increase platelet agg

Question 9

a1 effect

Answer 9

vasoconstriction, mydriasis, intestinal and bladder SM contraction

Question 10

B1 effect

Answer 10

increase HR, contractility, renin (BP!)

Question 11

B2 effect

Answer 11

vasodilation, bronchodilation, increase HR/contractility, increase INSULIN!!! (this is why beta blockers mask hypoglycemia– beta blockade results in low insulin, so glucose comes out in blood and seems to be at normal levels. but they still sweat)

Question 12

M1

Answer 12

CNS, enteric nervous system

Question 13

M2

Answer 13

decrease HR and contractility

Question 14

M3

Answer 14

increase exocrine secretions, peristalsis, bladder contraction, bronchoconstriction, miosis, accommodation

Question 15

D1

Answer 15

increase perfusion to kidney

Question 16

H1

Answer 16

nasal mucus, vascular permeability, contraction

Question 17

H2

Answer 17

gastric acid secretion

Question 18

V1

Answer 18

increase vasoconstriction

Question 19

V2

Answer 19

ADH receptor. H20 reabs in collecting tubules of kidney