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Pharmacology > Sympatholytic > Flashcards

Sympatholytic Flashcards

1
Q

ALPHA 2 AGONISM is the inhibition of further release of

A

Catecholamines

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2
Q

Centrally acting drugs are

A

Alpha 2 adrenoreceptor agonist

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3
Q

What is the ACTIVE FORM of methyldopa

A

a-methylNE

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4
Q

Methyldopa causes

A

Coomb’s positive hemolytic anemia

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5
Q

It is not recommended for chronic treatment

A

Clonidine

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6
Q

Effect of clonidine

A

Reduce BP and PVR

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7
Q

What happens when patient MISSED dose of ABRUPTLY STOPPED taking clonidine

A

Rebound hypertension

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8
Q

Clonidine is for

A

Hypertensive urgency

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9
Q

Effect of peripherally-acting alpha blockers

A

Vasodilation

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10
Q

What drug is best for COEXISTING CARDIOVASCULAR DISEASE

A

Beta blockers

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11
Q

Labetalol is a treatment for

A

Chronic hypertension
Hypertensive emergency

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12
Q

Labetalol causes

A

Orthostatic hypotension (a blocking activity)

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13
Q

What does carvedilol blocks

A

Alpha 1
Beta 1

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14
Q

What drugs have antioxidant properties

A

Carvedilol
Nebivolol

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15
Q

Antioxidant properties means

A

Cardioprotective effects

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16
Q

Nebivolol is a

A

Selective beta 1 blocker

17
Q

An ultra short acting beta blocker

A

Esmolol

18
Q

Stimulates the release of endothelial nitric oxide

A

Nebivolol

19
Q

A 3rd gen beta blocker

A

Carvedilol

20
Q

Best for patients with coexisting cardiovascular disease

A

Carvedilol

21
Q

Is carvedilol a first line treatment?

A

No

22
Q

Increase nitric oxide will lead to

A

Relaxation of vascular smooth muscle

23
Q

Activation of SANS will lead to

A

Increase blood glucose levels

24
Q

Activation of beta 2 receptors in the liver facilitates

A

Glycogenolysis

25
Q

Precautions of sympatholytics

A

Use cautiously with diabetic patients
- masks hypoglycemic symptoms
- delay recovery

26
Q

Adverse effects of sympatholytics

A

Orthostatic hypotension (except a-blocking)
More likely than a placebo
Not for physically active patients (decrease stamina)

Pharmacology (5 decks)

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