Surgery: Subspecialty Flashcards
Patient with hypertension and hypokalemia.
- Aldo:renin > 20
- Failed salt suppression test
Dx, next step, tx?
Primary hyperaldo (Conn’s)
Next step: CT/MRI and Adrenal vein sampling
Tx: resection
Old man with atherosclerosis, or young woman with fibromuscular dysplasia who has Hypertension and Hypokalemia.
- Aldo:renin < 10
Dx, next step, tx?
Renal Artery Stenosis
Next step: U/S doppler and Angiogram
Tx:
- For old patient: ACE-I, ARBs, or aldo antagonist (e.g., spironolactone)
- For young patient: stent
Paroxysms of BP elevation, Headache, Palpitations, Perspire (transpiration).
Dx, next step, tx?
Pheochromocytoma
Next steps:
- Urinary vanillylmandelic acid (VMA)
- Unrianry metanephrines
- CT scan/MRI
- Adrenal vein sampling
Tx:
- First alfa blockade
- Then beta blockade
- Then resection
Patient with
- Hypertension
- DM
- Women
- Buffalo hump
- Purple striae
- Moon facies
Next step?
Next steps:
- 24 hr free urine cortisol
- Low dose dexamethasone test (low then high)
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
Dx, Nex steps?
Cushing’s syndrome
Next step: ACTH levels
“low then high:” low dose DST –> ACTHen –> high dose DST
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- Low ACTH
Dx, Nex steps, tx?
Adrenal tumor
Nex steps: MRI/CT scan
Tx: resect
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- High ACTH
Dx, Nex steps?
High dose dexamethasone test
“low then high:” low dose DST –> ACTHen –> high dose DST
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- High ACTH
- High cortiso after high dose dexamethasone test (failed)
Dx, Nex steps?
Ectopic ACTH production (pananeoplastic sd)
Next steps: CT of lung, abdomen, pelvis
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- High ACTH
- Low cortisol after high dose dexamethasone test
Dx, Nex steps, tx?
Cushing’s disease
Next steps: MRI or CT abdomen
Tx: resection
- Torso HTN
- Legs hypotension
- Claudication
- Warm upper extremities, cold lower extremities
- Rib-notching (because of collaterals are formed)
Dx, Nex steps, tx?
Coarctation of aorta
Dx: angiogram
Tx: resect and reanastomose
Old, male with CAD, Chest pain, CHF, Syncope.
Systolic murmur crescendo-decrescendo murmur at the 2nd space-right sternal border (improves with valsava, worsens with leg raise). Radiated to carotids
Dx, next step, tx?
Aortic Stenosis
Dx: Echo
Tx: replacement + CABG
Holosystolic murmur at the apex, improves with Valsalva, radiates to the axial.
Dx, possible cause, next step, tx?
Mitral Regurgitation
Cause: Infection (endocarditis), infraction (papilary muscle/chordae tendinae rupture)
Dx: Echo
Tx: Replacement
Cardiogenic shock, flash pulmonary edema, chest pain.
Rumbling, blowing decrescendo diastolic murmur at the 4th intercostal space-left sternal border
Dx, next step, tx?
Aortic Regurgitation
Dx: Echo
Tx: Replacement + CABG
Young patient with CHF, AFibv.
Diastolic murmur on the apex “rumbling with opening snap”
Dx, possible cause, next step, tx?
Mitral Stenosis
Cause: Rheumatic disease
Dx: Echo
Tx: Balloon valvuloplasty (unique), then replacement
Diference between valve types
Bovine (organic)
- Last < 10 yrs
- No anticoagulation needed
Mechanical
- Last 10–20 yrs
- Need anticoagulation (warfarin, target INR 2.5–3.5)
Obese patient, HTN, DM, smoker, high cholesterol with Substernal pain, Worse with exercise, Improve with nitroglycerin or rest.
An NSTEMI is Dx and he goes to the cath where 1–2 vessels are compromised
Next step?
Angioplasty (PCI) + Clopidogrel
Obese patient, HTN, DM, smoker, high cholesterol with Substernal pain, Worse with exercise, Improve with nitroglycerin or rest.
An STEMI is Dx and he goes to the cath where left mainstem or 3+ vessels are compromised
Next step?
CABG
HTN, DM, smoker, high cholesterol with Shiny shins, Loss of hair, ↓ pulses, ↓ temp.
Dx, next steps, tx and f/u?
Peripheral vascular disease
Next steps:
- Ankle-brachial index (ABI)
- Doppler
- CT angiogram
Tx:
- Above the knee or small lesion: Angioplasty/stent
- Everything else: bypass
F/U: Medical treatment
BB/ACE-i, A1C< 7&, Smoking cessation, Statin, ASA or clopidogrel
Interpretation of Ankle-brachial index (ABI) in PVD
- 1.0–1.4: normal
- 0.9–1.0: ambiguous –> follow up with exercise ABI
- 0.8–0.9: mild
- 0.4–0.8: moderate
- < 0.4: severe
Patient at the ER with Pulselessness, Pale, Pokolothermia (cold limb), Pain, Paresthesia, Paralysis.
Dx, next steps, tx and f/u?
Acute limp ischemia (ALI)
Next steps:
- Doppler
- Angiogram
Tx: Embolectomy, or tPA
F/U: What out for compartment syndrome after tx
Male patient, older > 65, history of smoking, asx pulsatile mass, +/- back pain.
Dx, next step?
Abdominal aortic aneurysm (AAA)
Next step: U/S (screen men > 65; women > 65 with history of smoking)
Tx of Abdominal aortic aneurysm (AAA)?
- 3–4 cm, Diagnosis, Screen q2y
- 4–5 cm, Worrisome, Screen q1y
- 5–5.4 cm, High Risk, Screen q6mo
- > 5.5 cm, Danger, Operate (Endovascular aneurysm repair/open)
- > 0.5 cm/6 mo, Danger, Operate (Endovascular aneurysm repair/open)
Patient with tearing chest pain that radiates to the back, asymmetric BP between arms, widened mediastinum on CxR.
Dx, next step, tx?
Aortic dissection
Next step: CT angiogram
- MRI or TEE if CT angiogram can’t be done (e.g., CKD)
Tx:
- Type A (ascending): operate (evaluate for aortic valve replacement)
- Type B (descending): medical tx with IV beta-blockers
Risk factors for aortic dissection
HTN, marfan, syphilis
Causes of amblyopia
- Strabismus
- Congenital cataracts
Kid with light reflected differently between eyes (not at the center)
Dx, Tx?
Strabismus
Patch the good eye, glasses
Causes of congenital cataracts
- TORCH infection
- Galactosemia
When performing the red reflex, instead of red you see white in a pediatric patient.
Dx, tx, and associated problem?
Retinoblastoma
Tx: surgical
F/U: osteosarcoma
Pediatric patient in the neonatal unit with vascular growths on the retina.
Dx. tx?
Retinopathy of prematurity
Tx: laser ablation
F/U: bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis
Newborn who received Ppx with drops of silver nitrate who develops non-purulent bilateral eye discharge.
Dx?
Chemical conjunctivitis produced by silver nitrate.
The ppx should be done with erythromycin
5 days old baby with purulent bilateral eye discharge.
Dx, next steps, tx?
Gonorrhea
Next steps:
- Chocolate agar
- PCR
Tx: Ceftriaxona IM
10 days old baby with watery, then purulent, then bloody eye discharge. First unilateral, then bilateral.
Dx, next steps, tx?
Chlamydia
Next steps:
- Chocolate agar
- PCR
Tx: Erythromycin PO
Patient who was watching a movie and after that has pain in the eye, eye pain, Headaches. On physical Rigid eyeball and Non-reactive dilated pupil.
Dx, next step, tx?
Closed angle glaucoma
Next step: measure eye pressure
Tx: Constrict pupil • Alfa-2 agonist drops • Beta blockers drops Diuretics Emergent surgery to realise pressure
F/U: NEVER GIVE ATROPINE
Patient who was inflammation around the eye and can move it.
Dx?
periorbital cellulitis
Patient who was inflammation around the eye and can’t move it.
Dx, next step, tx?
Orbital Cellulitis
Next step: CT scan
Tx: surgical drainage + Abx
F/U: If DM/DKA consider mucormycotic and treat with amphotericin B
Patient who refers seeing floaters and then a curtain over vision. No pain in the eyer
Dx?
Retinal Detachment
Patient who refers curtain over vision that comes a goes. No pain in the eye.
Dx?
Amorousis fugax (sign of retinal artery occlusion
Patient who refers curtain over vision. No pain in the eye. On physyucal no other FND are seen. In fundoscopy you see Cherry red spots in the fovea
Dx, tx?
Retinal A. Occlusion
Tx:
- Intraarterial tPA
- Hyperventilation
Chronic progressive loss of central vision. On fundoscopy you see hemorrhages or fluid.
Dx?
Wet Macular degeneration
Chronic progressive loss of central vision. On fundoscopy you see pigment changes.
Dx, tx?
Macular degeneration
Tx: supportive care, no specific tx
Patient who was asx and suddenly develops the worst headache of his life. A few days ago he had a headaches wich resolved with pain medications.
Dx, next steps?
Subarachnoid hemorrhage
Next steps:
- Non-contrast CT scan showing bleeding within the meninges but not in the cerebral tissue
- Lumbar puncture (LP) if CT is negative despite high suspicion: Xanthochromia (yellowish CSF)
- CT angiogram/ MR angiogram/angiography
Patient who was asx and suddenly develops the worst headache of his life. A few days ago he had a headaches wich resolved with pain medications.
Non-contrast CT scan showing bleeding within the meninges but not in the cerebral tissue
Tx?
Subarachnoid hemorrhage
Bleeding control o BP < 140/90 with IV BB or CCB o Coil or clipping Hydrocephalus o Serial LP o VP shunt Seizures ppx (e.g., levetiracetam) ↓ ICP o Hypertonic solutions like mannitol o Elevate head of bed o Hyperventilate Late complications (5–7 d) Vasospasm ppx with CCB
F/U: CT scan to evaluate changes in hemorrhage
Patient with hx of HTN who develops headache, n/v and FND.
Non- contrast CT scan shows Intraparenchymal hemorrhage
Tx?
↓ ICP • Hypertonic solutions like mannitol • Elevate head of bed • Hyperventilate Craniotomy Evacuate the hematoma
F/U: CT scan to evaluate changes in hemorrhage and midline shifts
CT scan showing calcification of sella in a kid.
Dx?
Craniopharyngioma
Patient with FND, Seizure, Headache worse in AM, Progressive N/V.
CT scan shows calcified mass from the dura
Dx, tx?
Meningioma
Tx: resection (curative)
Patient with FND, Seizure, Headache worse in AM, Progressive N/V.
CT scan/ MRI ring enhancing lesion that crosses the midline
Dx, tx?
Glioblastoma multiforme (bad prognosis)
- Steroids (palliative)
- Seizure ppx (e.g., lamotrigine, phenitoin, levetiracetam)
Old male with urinary obstructive sx (hesitancy, frequency, failure to empty). On DRE you feel a firm nodular prostate.
PSA really elevated
Dx, next step, tx?
Prostate Cancer
Next step: Bx (transrectal vs transurethral)
Tx:
- Resection = radiotherapy = brachytherapy
- Antiandrogens (e.g., flutamide)
- GnRH analogs (e.g., leuprolide)
- Orchiectomy
F/U: PSA should decrease
- If PSA↑= Antiandrogens
- If PSA↑ and mets= radiation
Patient with painless hematuria. On U/S you see a mass on on the bladder.
Most common type of this cancer, next step, tx?
Transitional cell carcinoma (bladder ca)
Next step:
- Cystoscopy (best)
Tx: transurethral resection + intravesicular BCG/chemo (cisplatin)
- If invasive= cystectomy
25 y-o male with a painless mass in testicle, which doesn’t transilluminate.
Dx, next step, tx?
Testicular Cancer
Next step:
- U/S
- NEVER do Bx
Tx: orchiectomy
- If seminoma= Chemo (cisplatin)/radiation
- If non-seminoma
• Endodermal= follow-up with AFP
• Choriocarcinoma= follow-up with bHCG
• Teratoma= malignant in men!! (unlike in women)
Flank pain, Palpable mass and Painless hematuria.
Dx, next step, tx?
Renal Cell Cancer
Next step: CT scan (avoid Bx)
Tx: nephrectomy
- Chemo/radiation if mets
> 50 y-o male, Lower urinary track sx (hesitancy, dribbling, frequency, urgency, trouble emptying)
DRE showing a smooth rubbery prostate.
U/A and culture and negative
Dx, next step, tx
BPH
Next step: nothing, treat right away, no need of PSA or Bx
Tx:
- Open the urethra with alpha blockers (e.g., tamsulosin, doxazosin, terazosin)
- Prevent prostate growth with 5-alpha reductase inhibitors (e.g., finasteride)
- Transurethral resection of prostate (TURP)
Patient with sudden, spontaneous pain on testicule, horizontal lie of testicle, pain on elevation of testicle.
Dx, next step, tx?
Testicular Torsion
Dx: U/S doppler showing decrease vascular supply
Tx: Untwist/orchidectomy + Bilateral orchidopexy
Patient with sudden, spontaneous pain on testicule, Vertical lie, Relief of pain on elevation.
Dx, next step, tx?
Epididymitis
Mext step: normal U/S doppler
Tx:
- If < 35: ceftriaxone + azithromycin
- If > 35: ciprofloxacin
Old male with urgency, dysuria, frequency, fever, N/V. No CVA tenderness on physical exam, but really tender DRE.
Prostatitis
Next step: U/A + Urinary culture
Tx:
- Don’t repeat the DRE
- Bacterial: Abx
- Inflammatory: NSAIDs
Colicky flank pain that radiates to the groin.
Dx, next step, tx?
Kidney Stones
Next steps:
- U/A showing hematuria
- Non-contrast CT scan
- U/S if CT can’t be done
o Tx:
- < 0.5 cm: IVF + pain control
- 0.5–0.7 cm: add medical treatment (tamsulosin, amlodipine)
- 0.7–1.5 cm: stenting or lithotripsy
- > 1.5 cm: surgery
- Septic: nephrostomy
Patient with Pain, paresthesia, paralysis of first 3 digits. On physical worse sx with flexion of wrists, taping the nerve makes it worse.
DX, TX?
Carpal Tunnel syndrome
Tx:
- Splinting and NSAIDs
- Intraarticular steroids
- Surgery (make an EMG before)
Patient who during a football game had an injury of the hand while graving the jersey of another person. The patient can’t flex the finger (can be flexed passively without resistance).
Dx, tx?
Jersey Finger (tearing of the flexor tendon)
Tx: splining + NSAIDs, intraarticular steroids, surgery
Patient who during a football game had an injury of the hand while graving the ball. The patient can’t extend the finger (can be extended passively without resistance).
Dx, tx?
Mallet Finger (tearing of the extensor tendon)
Tx: splining + NSAIDs, intraarticular steroids, surgery
Patient who can’t extend the finger (when extended passively there is resistance and a pop sound).
Dx, tx?
Trigger Finger (stenosis tenosynovitis)
Tx: splining + NSAIDs, intraarticular steroids, surgery
Patient with tumb pain. On physical pain is worse when he makes a fist with the thumb under the fingers and with ulnar deviation.
Dx tx?
Dequervain’s tenosynovitis
Tx: splining + NSAIDs, intraarticular steroids (no surgery)
Patient with inability to extend, palpable fascia nodules on palm, palm in contraction.
Dx, tx?
Dupuytren contracture
Tx: surgery
Patient who had a penetratin injury on the pulp pf finger. He has a lot of pain and fever.
Dx, tx?
Felon (abscess of the pulp of the finger producing a mini compartment syndrome)
Tx: incision and drainage +/- antibiotics
Baby with persistent Clicky hip with barlow and ortolarni at 4 weeks.
Dx, next step, tx?
Developmental dysplasia of the hip (DDH)
Next step: U/S (4 weeks)
Tx: Harness
6 y-o patient with Insidious onset of antalgic walk .
Dx, next step, tx?
Legg-Calve-Perthes (avascular necrosis)
Next step: xR
Tx: Cast
13 y-o patient in Growth spurt who is Fat and consults because of Nontraumatic joint pain.
Dx, next step, tx?
Slip capital femoral epiphysis (SCFE)
Next step: Frog-leg xR
Tx: Surgery
Patient who can’t bear weight, Fever, ↑WBC, ↑ESR, ↑CRP.
Dx, next step, tx?
Septic Joint
Next step: Arthrocentesis with > 50,000 WBC
Tx: Drain + Abx
Patient with Hip pain after a viral illness who Can’t bear weight.
Dx, tx?
Transient Synovitis
Tx: Autoinflammatories
Teenage athlete with Knee pain and Tibial swelling.
Dx, tx?
Osgood Schlatters (osteocondrosis)
Tx: Stop exercise, or continue but they’ll have a palpable nodule
Teenage girl with and Positive Adam’s test.
Dx, next step, tx?
Scoliosis
Next step: xR
Tx:
- Brace can slow progression and prevent surgery
- Surgery for severe cases
Pediatric patient with Focal, atraumatic bone pain.
xR shows tumor in distal bone with sunburst pattern
Dx, path, next step, tx?
Osteosarcoma
Path: retinoblastoma gene
Next steps: MRI, Bx
Tx: resection
Pediatric patient with Focal, atraumatic bone pain.
xR shows Tumor in mid-shaft of bone with onion-skin appearance
Dx, path, next step, tx?
Ewing’s Sarcoma
Path: translocation 11, 22
Next steps: MRI, Bx
Tx: resection
When is an o Open reduction and internal fixation (ORIF) indicated in a pediatric fracture?
- Open Fx
- Comminuted Fx
- Involvement of growth plate
Patient who had trauma on the shoulder and it’s in adduction and externally rotated. Also he refers • Deltoid paresthesia.
Dx?
Anterior Dislocations of shoulder
Patient who was on a car accident and now has the Shoulder in adduction and internally rotated.
Dx?
Posterior dislocation of shoulder
Old Woman Falls onto an outstretched wrist. Wrist Fracture is dorsally displaced.
Dx?
Collis fracture
A person was blocking upward from a downward blow. On xR you see Ulnar fracture and Radius dislocation.
Dx?
Monteggia
A person was blocking downward from a downward blow . On xR you see Radius fracture and Ulnar dislocation.
Dx?
Galleazzi
- Falls onto an outstretched wrist
- Pain at the anatomic snuff box
Dx?
Scaphoid fracture
Tx of hip fracture?
- Femoral head fx: Head prosthesis
- Intertrocanteric fx: plates
- Shaft: rods
- Open: emergency washout
- While the surgery is performed: traction
Patient who had posterior trauma on the knee and has anterior draw sign.
Dx?
ACL rupture
Patient who had anterior trauma on the knee and has posterior draw sign.
Dx?
PCL rupture
Patient who has knee pain and click on extension.
Dx?
Meniscus injury
Patient who had ankle overeversion, has pain and swelling but can walk.
Dx?
Sprain
Patient who had ankle overeversion, has pain and swelling and can’t walk.
Dx?
Fracture
Back pain that is exacerbated by standing and walking and relieved with sitting and hyperfl exion of the hips.
Spinal stenosis.
Joints in the hand affected in rheumatoid arthritis.
MCP and PIP joints; DIP joints are spared.
Joint pain and stiffness that worsen over the course of the day and are relieved by rest.
Osteoarthritis
Genetic disorder associated with multiple fractures and commonly mistaken for child abuse.
Osteogenesis imperfecta.
Hip and back pain along with stiffness that improves with activity over the course of the day and worsens at rest.
Diagnostic test?
Suspect ankylosing spondylitis. Check HLA-B27.
Arthritis, conjunctivitis, and urethritis in young men.
Associated organisms?
Reactive (Reiter’s) arthritis. Associated with Campylobacter, Shigella, Salmonella, Chlamydia, and Ureaplasma.
A 55-year-old man has sudden, excruciating first MTP joint pain after a night of drinking red wine.
Diagnosis, workup, and chronic treatment?
Gout.
Joint fluid aspirate: Needle-shaped, negatively birefringent crystals
Chronic treatment with allopurinol or probenecid.
Rhomboid-shaped, positively birefringent crystals on joint fluid aspirate.
Pseudogout.
An elderly woman presents with pain and stiffness of the shoulders and hips; she cannot lift her arms above her head.
Labs show anemia and ↑ ESR.
Polymyalgia rheumatica.
An active 13-year-old boy has anterior knee pain. Diagnosis?
Osgood-Schlatter disease.
Bone is fractured in a fall on an outstretched hand.
Distal radius (Colles’ fracture).
Complication of scaphoid fracture.
Avascular necrosis.
Signs suggesting radial nerve damage with humeral fracture.
Wrist drop, loss of thumb abduction.
A young child presents with proximal muscle weakness, waddling gait, and pronounced calf muscles.
Duchenne muscular dystrophy.
A first-born female who was born in breech position is
found to have asymmetric skin folds on her newborn exam.
Diagnosis? Treatment?
Developmental dysplasia of the hip. If severe, consider a Pavlik harness to maintain abduction.
An 11-year-old obese African-American boy presents with sudden onset of limp pain. Diagnosis? Workup?
Slipped capital femoral epiphysis. AP and frog-leg lateral view.
The most common 1° malignant tumor of bone.
Multiple myeloma.