Surgery: Subspecialty Flashcards
Patient with hypertension and hypokalemia.
- Aldo:renin > 20
- Failed salt suppression test
Dx, next step, tx?
Primary hyperaldo (Conn’s)
Next step: CT/MRI and Adrenal vein sampling
Tx: resection
Old man with atherosclerosis, or young woman with fibromuscular dysplasia who has Hypertension and Hypokalemia.
- Aldo:renin < 10
Dx, next step, tx?
Renal Artery Stenosis
Next step: U/S doppler and Angiogram
Tx:
- For old patient: ACE-I, ARBs, or aldo antagonist (e.g., spironolactone)
- For young patient: stent
Paroxysms of BP elevation, Headache, Palpitations, Perspire (transpiration).
Dx, next step, tx?
Pheochromocytoma
Next steps:
- Urinary vanillylmandelic acid (VMA)
- Unrianry metanephrines
- CT scan/MRI
- Adrenal vein sampling
Tx:
- First alfa blockade
- Then beta blockade
- Then resection
Patient with
- Hypertension
- DM
- Women
- Buffalo hump
- Purple striae
- Moon facies
Next step?
Next steps:
- 24 hr free urine cortisol
- Low dose dexamethasone test (low then high)
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
Dx, Nex steps?
Cushing’s syndrome
Next step: ACTH levels
“low then high:” low dose DST –> ACTHen –> high dose DST
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- Low ACTH
Dx, Nex steps, tx?
Adrenal tumor
Nex steps: MRI/CT scan
Tx: resect
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- High ACTH
Dx, Nex steps?
High dose dexamethasone test
“low then high:” low dose DST –> ACTHen –> high dose DST
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- High ACTH
- High cortiso after high dose dexamethasone test (failed)
Dx, Nex steps?
Ectopic ACTH production (pananeoplastic sd)
Next steps: CT of lung, abdomen, pelvis
Patient with Hypertension, DM, Women, Buffalo hump, Purple striae, Moon facies .
- High 24 hr free urine cortisol
- Failed low dose dexamethasone test
- High ACTH
- Low cortisol after high dose dexamethasone test
Dx, Nex steps, tx?
Cushing’s disease
Next steps: MRI or CT abdomen
Tx: resection
- Torso HTN
- Legs hypotension
- Claudication
- Warm upper extremities, cold lower extremities
- Rib-notching (because of collaterals are formed)
Dx, Nex steps, tx?
Coarctation of aorta
Dx: angiogram
Tx: resect and reanastomose
Old, male with CAD, Chest pain, CHF, Syncope.
Systolic murmur crescendo-decrescendo murmur at the 2nd space-right sternal border (improves with valsava, worsens with leg raise). Radiated to carotids
Dx, next step, tx?
Aortic Stenosis
Dx: Echo
Tx: replacement + CABG
Holosystolic murmur at the apex, improves with Valsalva, radiates to the axial.
Dx, possible cause, next step, tx?
Mitral Regurgitation
Cause: Infection (endocarditis), infraction (papilary muscle/chordae tendinae rupture)
Dx: Echo
Tx: Replacement
Cardiogenic shock, flash pulmonary edema, chest pain.
Rumbling, blowing decrescendo diastolic murmur at the 4th intercostal space-left sternal border
Dx, next step, tx?
Aortic Regurgitation
Dx: Echo
Tx: Replacement + CABG
Young patient with CHF, AFibv.
Diastolic murmur on the apex “rumbling with opening snap”
Dx, possible cause, next step, tx?
Mitral Stenosis
Cause: Rheumatic disease
Dx: Echo
Tx: Balloon valvuloplasty (unique), then replacement
Diference between valve types
Bovine (organic)
- Last < 10 yrs
- No anticoagulation needed
Mechanical
- Last 10–20 yrs
- Need anticoagulation (warfarin, target INR 2.5–3.5)
Obese patient, HTN, DM, smoker, high cholesterol with Substernal pain, Worse with exercise, Improve with nitroglycerin or rest.
An NSTEMI is Dx and he goes to the cath where 1–2 vessels are compromised
Next step?
Angioplasty (PCI) + Clopidogrel
Obese patient, HTN, DM, smoker, high cholesterol with Substernal pain, Worse with exercise, Improve with nitroglycerin or rest.
An STEMI is Dx and he goes to the cath where left mainstem or 3+ vessels are compromised
Next step?
CABG
HTN, DM, smoker, high cholesterol with Shiny shins, Loss of hair, ↓ pulses, ↓ temp.
Dx, next steps, tx and f/u?
Peripheral vascular disease
Next steps:
- Ankle-brachial index (ABI)
- Doppler
- CT angiogram
Tx:
- Above the knee or small lesion: Angioplasty/stent
- Everything else: bypass
F/U: Medical treatment
BB/ACE-i, A1C< 7&, Smoking cessation, Statin, ASA or clopidogrel
Interpretation of Ankle-brachial index (ABI) in PVD
- 1.0–1.4: normal
- 0.9–1.0: ambiguous –> follow up with exercise ABI
- 0.8–0.9: mild
- 0.4–0.8: moderate
- < 0.4: severe
Patient at the ER with Pulselessness, Pale, Pokolothermia (cold limb), Pain, Paresthesia, Paralysis.
Dx, next steps, tx and f/u?
Acute limp ischemia (ALI)
Next steps:
- Doppler
- Angiogram
Tx: Embolectomy, or tPA
F/U: What out for compartment syndrome after tx
Male patient, older > 65, history of smoking, asx pulsatile mass, +/- back pain.
Dx, next step?
Abdominal aortic aneurysm (AAA)
Next step: U/S (screen men > 65; women > 65 with history of smoking)
Tx of Abdominal aortic aneurysm (AAA)?
- 3–4 cm, Diagnosis, Screen q2y
- 4–5 cm, Worrisome, Screen q1y
- 5–5.4 cm, High Risk, Screen q6mo
- > 5.5 cm, Danger, Operate (Endovascular aneurysm repair/open)
- > 0.5 cm/6 mo, Danger, Operate (Endovascular aneurysm repair/open)
Patient with tearing chest pain that radiates to the back, asymmetric BP between arms, widened mediastinum on CxR.
Dx, next step, tx?
Aortic dissection
Next step: CT angiogram
- MRI or TEE if CT angiogram can’t be done (e.g., CKD)
Tx:
- Type A (ascending): operate (evaluate for aortic valve replacement)
- Type B (descending): medical tx with IV beta-blockers
Risk factors for aortic dissection
HTN, marfan, syphilis
Causes of amblyopia
- Strabismus
- Congenital cataracts
Kid with light reflected differently between eyes (not at the center)
Dx, Tx?
Strabismus
Patch the good eye, glasses
Causes of congenital cataracts
- TORCH infection
- Galactosemia
When performing the red reflex, instead of red you see white in a pediatric patient.
Dx, tx, and associated problem?
Retinoblastoma
Tx: surgical
F/U: osteosarcoma
Pediatric patient in the neonatal unit with vascular growths on the retina.
Dx. tx?
Retinopathy of prematurity
Tx: laser ablation
F/U: bronchopulmonary dysplasia, intraventricular hemorrhage, necrotizing enterocolitis
Newborn who received Ppx with drops of silver nitrate who develops non-purulent bilateral eye discharge.
Dx?
Chemical conjunctivitis produced by silver nitrate.
The ppx should be done with erythromycin
5 days old baby with purulent bilateral eye discharge.
Dx, next steps, tx?
Gonorrhea
Next steps:
- Chocolate agar
- PCR
Tx: Ceftriaxona IM
10 days old baby with watery, then purulent, then bloody eye discharge. First unilateral, then bilateral.
Dx, next steps, tx?
Chlamydia
Next steps:
- Chocolate agar
- PCR
Tx: Erythromycin PO
Patient who was watching a movie and after that has pain in the eye, eye pain, Headaches. On physical Rigid eyeball and Non-reactive dilated pupil.
Dx, next step, tx?
Closed angle glaucoma
Next step: measure eye pressure
Tx: Constrict pupil • Alfa-2 agonist drops • Beta blockers drops Diuretics Emergent surgery to realise pressure
F/U: NEVER GIVE ATROPINE
Patient who was inflammation around the eye and can move it.
Dx?
periorbital cellulitis
Patient who was inflammation around the eye and can’t move it.
Dx, next step, tx?
Orbital Cellulitis
Next step: CT scan
Tx: surgical drainage + Abx
F/U: If DM/DKA consider mucormycotic and treat with amphotericin B
Patient who refers seeing floaters and then a curtain over vision. No pain in the eyer
Dx?
Retinal Detachment
Patient who refers curtain over vision that comes a goes. No pain in the eye.
Dx?
Amorousis fugax (sign of retinal artery occlusion
Patient who refers curtain over vision. No pain in the eye. On physyucal no other FND are seen. In fundoscopy you see Cherry red spots in the fovea
Dx, tx?
Retinal A. Occlusion
Tx:
- Intraarterial tPA
- Hyperventilation
Chronic progressive loss of central vision. On fundoscopy you see hemorrhages or fluid.
Dx?
Wet Macular degeneration
Chronic progressive loss of central vision. On fundoscopy you see pigment changes.
Dx, tx?
Macular degeneration
Tx: supportive care, no specific tx