Superficial layers of the upper limb Flashcards
What are the 2 layers of skin?
Dermis and epidermis
What is the function of the epidermis?
Physical and chemical barrier between the body and its exterior environment
What is the function of the dermis?
Provides structural and nutritional support
What percentage of the total body mass comes from the skin?
16%
What is the average total surface area of the skin?
1.8m2
Why is the epidermis known as a stratified squamous epithelium?
It consists of many layers of closely packed cells, the most superficial of which are flattened and filled with keratin.
What are the 4 layers of epidermis from superficial to deep?
Stratum corneum
Stratum granulosum
Stratum spinosum
Stratum basale
What is the additional layer of epidermis only found in some areas?
Where is it located?
Stratum lucindum
Hands and feet, between corneum and granulosum
Describe the stratum basale
Single layer of cells which continually divide to replace those shed from skin
Where re melanocytes located?
What is their function?
Stratum basale
Produce the pigment melanin to protect from UV rays
Describe the stratum spinosum
Thickest layer with ‘prickle cells’ which are linked by numerous processes
Describe the stratum granulosum
Cells gradually accumulate keratohyalin granules which eventually overfill cells, destroying the nuclei and organelles
Describe the stratum corneum
Thickest in palms and soles and contains dead keratinocytes or squames which are continually shed from the surface
Describe the stratum lucindum
Only present in hands and feet. Contains tonofibrils (densely packed keratin filaments)
Which layer of the epidermis contains the most flattened cells?
Stratum corneum
How is the epidermis attached to the dermis?
Interlocking of its downward projections (epidermal ridges or pegs) with upward projections from the dermis (dermal papillae) at a site referred to as the dermoepidermal junction
Why are epidermal pegs structurally important?
They allow the skin to withstand abrasive forces and prevent the formation of blisters
What gives the dermis its strength?
The arrangement of its elastic and collagen fibres
Where is the dermis thin?
Eyelids