Summary Session Flashcards
List 4 reasons animals require matter for energy.
Homeostasis, metabolism, growth, and reproduction
Which two organic molecules are the primary fuels?
a. Carbohydrates
b. Proteins
c. Fats
d. Nucleic acids
e. Both a and c
f. Both a and b
g. All of the above
E
Which two monomers form the following disaccharides and polysaccharides?
Sucrose:
Maltose:
Lactose:
Starch:
Glycogen:
Cellulose:
-Sucrose: glucose + fructose
Maltose: glucose + glucose
Lactose: glucose + galactose
Starch: chain of glucoses
Glycogen: long chain of glucoses with branches
Cellulose: long chain of glucose with different linkage (main component of cell walls)
The build-up of which molecule causes atherosclerosis?
a. Carbohydrates
b. Lipids
c. Nucleic acids
d. Proteins
B
What is the difference between saturated and unsaturated lipids?
-Saturated fats have no bend in their molecular structure (no double bonds); solid at room temp
Unsaturated fats have a bend in their molecular structure (caused by a double bond); liquid at room temp
There are …..essential amino acids,….. essential vitamins, and ……
essential minerals.
-8 A.A, 13 vitamins, large number of minerals
Which of the following is the correct pathway food travels through your digestive system?
a. Mouth, esophagus, stomach, large intestine, small intestine, anus
b.Mouth, nasal cavity, pharynx, esophagus, stomach, small intestine, large
intestine, anus
c. Mouth, pharynx, esophagus, stomach, small intestine, large intestine, rectum
d. Mouth, cardiac sphincter, stomach, small intestine, large intestine, anus
e. Mouth, pharynx, esophagus, stomach, small intestine, large intestine, anus
E
List the four layers of the vertebrate gut from the outermost to the innermost.
-Serosa, muscularis, submucosa, mucosa
Which layer contributes the most to peristalsis?
Muscularis: Formed by circular layer (constricts gut diameter) and longitudinal layer (shortens and widens gut): push contents through gut (peristalsis)
Define sphincter.
-Circular smooth muscle that form valves to prevent backflow of products
-Separate major parts of digestive tract
What are the 4 major sphincters and where are they located?
Cardiac sphincter (lower esophageal): between esophagus and stomach
Pyloric sphincter: between stomach and small intestine
Ileocecal valve: between ileum (last portion of your small intestine) and the colon (first portion of your large intestine)
Anal sphincter: between large intestine and exterior
Where is the location of Gastrin, what is it stimulated by and what is its function?
-stomach
-chemoreceptors in stomach
-stimulates the stomach to secrete HCl and pepsinogen
Where is the location of GIP, what is it stimulated by and what is its function?
-Secreted by cells in the mucosa of the small intestine; receptors for it are in the pancreas
-food (glucose() in the first part of the small intestine(duodenum)
-stimulates insulin release by the pancreas
Where is the location of CCK, what is it stimulated by and what is its function?
-synthesized by cells in the mucosal epithelium of the small intensive and secreted in the duodenum
-fat or protein rich chyme entering the duodenum
-inhibits gastric activity, allow nutrients to be digested in duodenum, absorbed, causes release of digestive enzymes from pancreas and bile froim gall bladder. Rapid inhibition of eating
Where is ghrelin, what is it stimulated by and what is its function
Produced in stomach and in cells in the pancreas, act on hypothalamus
Fasting and low carb diet
Stimulates hunger
Where is leptin, what is it stimulated by and what is its function
-produced by the adipose tissue,acts on receptors in the hypothalamus
-Adipose cells full of fat
-signals to the brain that the body has had enough to eat
Where is PYY, what is it stimulated by and what is its function?
-secreted by the small intestine
-released in response to feeding
-suppress appetite
Explain the process of fat digestion in the small intestine in 3 steps
-liver secretes bile that emulsifies fat
-bile salts and movement of small intestine form micelles of fat, accessible by lipases
-lipases hydrolyze fats inside the micelles
Digestion is regulated by the ____________________ nervous system.
a. Enteric Nervous System (ENS)
b. Parasympathetic
c. Peripheral nervous system (PNS)
d. Autonomous
e. All of the above
E
What cells secrete H+ and Cl-
-parietal cells
What is the function and source of Growth Hormone (GH)
-stimulates bone and muscle growth
-anterior pituitary
What is the function and source of prolactin
-stimulates milk production and secretion
-anterior pituitary
What is the function and source of adrenocorticotropic hormone (ACTH)
-stimulates adrenal cortex to secret glucocorticoids
-anterior pituitary
What is the function and source of Thyroid stimulating hormone (TSH)
-stimulates the thyroid to produce thyroid hormones
-anterior pituitary
What is the function and source of Lutenizing hormone(LH)
-stimulates ovulation in females and testosterone synthesis in males
-anterior pituitary
- What is the function and source of follicle stimulating hormone
-stimulates folicle maturation in females and spermatogenesis in males
-anterior pituitary
What is the function of oxytocin and source
-hypothalamus but stored in posterior pituitary
-stimulates the uterine contraction during labor and milk secretion during lactation
What is the function and source of thyroid hormone
-stimulates metabolic activity
-thyroid
What is the function and source of glucocorticoids
-increase blood glucose levels and decrease protein synthesis
-adrenal cortex
What is the function and source of mineralcorticoids
-increase water reabsorption in kidneys
-adrenal cortex
What is the source and function of epinepherine and norepinephrine
-increase blood glucose level and heart rate
-adrenal medulla
What is the source and function of testosterone
-maintains male secondary sexual characteristics
-testes
What is the source and function of estrogen
-maintains female secondary sexual characteristics
-ovary/placenta
What is the source and function of progesterone
-promotes growth and maintenance of endothelium (uterine lining)
-ovary/placenta
What is the source and function of melatonin
–sleep/wake
-seasonal patterns
-pineal gland
What is a tropic hormone
-hormone that regulates hormone secretion by another endocrine gland
Explain the oxytocin positive feedback mechanism
-Oxytocin stimulates the muscle contractions that push the baby through the birth canal. The
release of oxytocin results in stronger contractions during labor. The contractions intensify and
increase until the baby is outside the birth canal. When the stimulus to the pressure receptors
ends, oxytocin production stops and labor contractions cease.
Why are most hormones involved in negative feedback mechanisms rather than positive feedback mechanisms?
Positive feedback mechanisms control self-perpetuating events that can be out of control and
do not require continuous adjustment. Whereas, negative feedback mechanisms control highly
regulated bodily functions such as homeostasis. In negative feedback the hormone feeds back
to decrease its own production which brings things back to normal whenever they start to
become too extreme
Which hormone is associated with a “runner’s high” (a cease of pain experienced by
some individuals during strenuous running)?
a. Oxytocin
b. Endorphins
c. Substance P
d. ACTH
e. Cortisol
B
A surge in which hormone is responsible for ovulation?
a. LH
b. FSH
c. Progesterone
d. Estradiol
e. No surge is involved in ovulation
A
Which 3 classes of wbc can bone marrow stem cells become?
(1) Granulocytes: presence of granules in their cytoplasm (neurtrophils, eosinophils, mast
cells and basophils are all types of granulocytes)
(2) Monocytes: clear cytoplasm, larger; migrate to site of infection and divide into macrophages and dendritic cells
(3) Lymphocytes: NK cells, T cells, B cells
What is an antigen?
Viruses, foreign cells and certain molecules that are capable of triggering immune reactions by
lymphocytes
What is an epitope?
The precise molecular group of antigen that defines its specificity and triggers the immune response
How does B cell activation occur? (Antibody-Mediated Immune Response)
(1) Clonal selection, antigen binding → engulf pathogen
(2) Antigen processing, presentation of antigen to eventual helper t cell(s)
(3) T helper cell interaction, link, secrete interleukins
(4) B cell activation
(5) Clonal expansion
(6) Production of plasma cells (secrete antibodies), memory B cells
How can antibodies kill invading bacteria?
● Agglutination of bacteria into a clump, preventing them from infecting cells
● Stimulating the complement system
● Enhancing phagocytosis
● Allowing the innate immune response to initiate membrane response complexes
How do T cells recognize an antigen and become activated? (Cell Mediated Immune Response)
(1) Antigen must be processed by antigen presenting cells: APC’s (dendritic cells, B cells,
and macrophages) → complexed with other proteins (MHC) and transported to the cell
membrane of the APC
(2) APC presents antigen to T cell and activates T cell → colonel expansion
(3) Production of different T cells
When the T cells are activated, what do they differentiate into?
● Memory T cells → future interaction with antigen
● T helper cells (CD4 and MHCII) → B and T cell growth/activation, release chemical
factors
● Cytotoxic T cells (CD8 and MHCI) → kill specific cells, perforins and granzymes
Which of the following can be a part of the adaptive immune system?
i. inflammatory response
ii. NK cells
iii. Pyrogens
iv. Antibodies
a. i, ii, iii, iv
b. i, iii
c. ii, iv
d. ii, iii, iv
e. iv only
C
What is involved in the release of histamine?
a. Mast cells
b. Basophil
c. Eosinophil
d. Both a and b
e. All of the above
D
How does an attack complex kill a pathogen?
a. Stops cell wall formation
b. Inhibits DNA synthesis
c. Reduces protein synthesis
d. Creates pores on membrane of pathogen
e. Induces a fever
D
How does the COVID-19 virus enter host cells?
- Glycoprotein spike on COVID virus binds to angiotensin converting enzyme II (ACE2) ,
which is the receptor in the host cell - This induces endocytosis of virion particle, and catalyzes the fusion between host and
viral membranes, allowing penetration of the virus genome into host cytoplasm - Virus RNA uses host cell to create new virus RNA and assemble new viral particles
Pulmonary embolisms and strokes are possible effects of COVID-19. How does
COVID-19 cause these blood clots?
a. Rush of cytokines raises clotting factors in blood
b. Inflammation (severe inflammation can trigger clotting)
c. Pneumonia
d. Ground glass opacity
e. Both a and b
E
Where is ACE2 most abundant?
a. Large intestine
b. Lungs
c. Endothelial and smooth cells of the blood vessels
d. Small intestine
e. Both b and d
E
Communication within neurons is _____, communication between neurons is ______.
a. excitatory, inhibitory
b. inhibitory, excitatory
c. chemical, electrical
d. electrical, chemical
C
Where would you see Nodes of Ranvier?
a. On the axon
b. On the cell body
c. On the dendrites
d. A and C
A
Explain how the different activation states of sodium channels contribute to the absolute refractory period.
a. When sodium channels are inactivated, they must fully close before opening
again. Thus, the inactivation state is one in which it is completely impossible to
respond to another stimulus, because the sodium channels just cannot open.
They only go back to the closed state (and have the ability to reopen) when the
cell is around resting potential again. There is no way for another AP to be
generated when the sodium channels are inactivated, thus it is an absolute
refractory period.
How does sodium contribute to the relative refractory period?
a. Some (but not all) of the sodium channels have returned to their closed/resting
state = they are able to open again!