Summary 2 - MSK Flashcards

1
Q

Describe acute compartment syndrome

A

Condition in which the circulation to, and functions of tissues in, closed space are compromised by increased pressure within space
Most common causes are haemorrhages into space by fractures

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2
Q

What are the symptoms and signs of acute compartment syndrome?

A

Pain which is out of proportion to injury, pain on passive stretch, altered sensation, weakness and swelling
Paraesthesia, pale, pulseless, paralysis and cold
Elevated compartment pressure within 30mmHg of diastolic

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3
Q

What is the treatment for acute compartment syndrome?

A

Open constriction dressings to skin, treat with emergency fasciotomy of all affected compartments

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4
Q

Describe osteosarcoma

A

Type of primary bone cancer which mostly diagnosed in teenagers and young adults
MRI is the investigation of choice

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5
Q

What are the symptoms of osteosarcoma?

A

Pain, loss of function, swelling, pathological fractures, joint effusion, deformity and neurovascular effects
Pain is a deep boring ache which is worse at night
Deep seated mass

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6
Q

What is the treatment for osteosarcoma?

A

Chemo, surgery and RT
Surgery - lib is salvageable in most cases

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7
Q

Describe metastatic bone disease

A

Secondary bone tumour which is 25x more common than primary
Bone is most common site for metastasis
Site is vertebrae> proximal femur> pelvis> ribs> sternum> skull

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8
Q

What are the 7 most common primary cancers which metastasis to bone?

A

Lung, breast, prostate, kidney, thyroid, GI tract and melanoma

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9
Q

What is the treatment and management for metastatic bone cancer?

A

Prevention of pathological fracture - embolization and conservatively if non-weight bearing part
Prophylactic fixation
RT, chemo and surgery

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10
Q

Describe developmental dysplasia of the hip (DDH)

A

Hip joint is misaligned due to ball + socket of hip joint not being fully developed correctly leading to instability
More girls affected and left hip is more common

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11
Q

What are the symptoms and signs of developmental dysplasia of the hip?

A

Ortolani’s sign, Barlow’s sign, hamstring sign and piston motion sign
Can lead to pain, OA of hip and back, and limp

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12
Q

What is the management and treatment for DDH?

A

Under 3 months - Pavlik harness
Closed reduction and spica cast
Over 1 - open reduction and capsule reefing
Over 18 months - open reduction and femoral shortening

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13
Q

Describe Perthes disease

A

Rare childhood condition where part of the femur dies due to lack of blood supply - collapse of bone
Pathological AVN of hip
More males and primary school age

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14
Q

What is the symptoms and signs of Perthes disease?

A

First symptoms is a limp or change in walk
Knee pain on activity, stiff knee joint, systemically well, inflammation of hip and no injury associated to pain
Small sclerotic epiphysis seen on X-ray

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15
Q

What is the management and treatment for Perthes disease?

A

Maintain hip motion, analgesia and restrict painful activities
Supervised neglect in most cases
Consider osteotomy if over 7 years

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16
Q

Describe Slipped under femoral epiphysis (SUFE)

A

Affects the physis of proximal femur in adolescents
Classified on magnitude of slip - stable or unstable (can’t weight bear)
More teenage boys affected - many overweight

17
Q

What are the symptoms and signs of SUFE?

A

Left groin pain for around3 months, short, externally rotated and possibly painful to weight bear
Externally rotated posture and gait. Reduced internal rotation esp. in flexion

18
Q

What is the treatment for SUFE?

A

Stable slips are usually pinned in situ and severe unstable slips are considered for open reduction but high AVN risk

19
Q

Describe Paget’s disease of bone

A

Localised disorder of bone turnover which has increased bone resorption followed by increased bone formation - disorganised bone
Strong genetic component

20
Q

What are the symptoms and signs of SUFE?

A

Bone pain, bone deformity, excessive heat over Paget’s joint and neurological complications like nerve deafness
Isolated elevation of serum alkaline phosphatase

21
Q

What is the management and treatment for Paget’s disease?

A

No need to treat asymptomatic unless includes skull or needs surgical intervention
IV bisphosphonate therapy
Ca and Vitamin D supplements
Physio, OT and aids

22
Q

Describe Rickets and osteomalacia

A

Rickets - affects bone development in children
Osteomalacia - similar condition but in adults where epiphyseal plates are closed
Muscle function also impaired from low Vit D
Low Ca, low vitamin D, raised PTH and raised alkaline phosphatase

23
Q

What are the signs and symptoms of rickets?

A

Stunted growth, large forehead, odd curve to spine, wide joints, odd shaped legs, large abdomen and sore bones causing waddling
Bones more prone to breaking

24
Q

What are the signs and symptoms of osteomalacia?

A

Bone pain, muscle weakness and fragile bones which are more prone to fractures

25
What is the treatment for rickets and osteomalacia?
Increasing intake of vitamin D and calcium - diet and supplements
26
Describe osteogenesis imperfecta
Genetic disorder of connective tissue characterised by fragile bones from trauma and acts of daily life Defects in collagen Broad clinical diagnosis
27
What are the symptoms and signs of osteogenesis imperfecta?
Type 1 - muscle weakness and bone fractures Type 2 - babies can't breathe Type 3 - broken bones at birth Type 4 - bone fractures and mild deformity Growth deficiency, blue sclera, scoliosis, defective tooth formation and easy bruising
28
What is the management and treatment for osteogenesis imperfecta?
Surgical to treat fractures Medical to prevent fractures - IV bisphosphonates Genetic counselling and educational adaptions
29
Describe osteoporosis
Metabolic bone disease characterised by low bone mass and micro-architectural deuteriation of bone tissue Leads to bone fragility and increase in fractures - most common is wrist, hip and vertebrae
30
What are the investigations for osteoporosis?
Result on DXA bone scanning less than 2.5 SDs below the young adult mean in post-menopausal women or thin bones have increased risk of fracture Q fracture - risk assessment tool
31
What is the management and treatment for osteoporosis?
Ensure good calcium and vitamin D status DXA scanning - if 15% 10 year risk then make treatment threshold Medications - antiresorptive therapies (HRT, SERMs, bisphosphates and Denosumab) and anabolic therapies (teriparatide)
32
Describe cerebral palsy
Permanent and non-progressive motor disorder due to brain damage before birth or during the first 2 years of life Can be spastic, athetoid, ataxia, and mixed GMFCS - motor function classification
33
What are the signs and symptoms of cerebral palsy?
Spasticity, lack of voluntary control, weakness, poor co-ordination and impaired senses Can have dynamic or fixed contractures and dislocations Hip displacement is common
34
What is the non-surgical treatment for cerebral palsy?
Physio Spasticity management - Baclofen oral, diazepam, botulinum toxin and intra-thecal pump of Baclofen
35
Describe congenital talipes eqinovarus
Club feet Deformity of foot presenting in infants CAVE - cavus, adductus, varus hindfoot, and equinus hindfoot 95% treated successfully and are left pain free and mobile feet
36
What is the treatment for congenital talpies equinovarous (CTEV)?
Strapping for positional talipes only Serial casting and surgery Correct equinus - percutaneous tenotomy of Achilles tendon